Updated and expanded to reflect the growing literature on this widespread disorder, this second edition has a new editor and uses the same approach as the first, pairing a chapter on the basic science of a disorder followed by a one on its clinical aspects.

Osteoporosis is a widespread disorder with significant worldwide health and economic impact. In the second edition of the highly successful Osteoporosis: Pathophysiology and Clinical Management, new editor Robert A. Adler, MD, uses the same approach as the first edition, pairing a chapter on the basic science of a disorder followed by a chapter on its clinical aspects. Updated and expanded, this second edition includes many new chapters reflecting the growing literature on osteoporosis. New topics cover such areas as methods of bone imaging, screening for osteoporosis, adherence to therapy, and even a novel and exciting chapter on osteoporosis in men, to name just several. In Osteoporosis: Pathophysiology and Clinical Management, Second Edition, leading experts in a variety of fields have once again provided a wealth of invaluable, state-of-the-art information to illuminate the major scientific and clinical aspects of osteoporosis.

Comprehensive, expanded second edition, including a new chapter on osteoporosis in men Details the basic as well as clinical aspects of diagnosing and managing osteoporosis Covers state-of-the-art methods for bone imaging and screening for osteoporosis Offers new coverage on adherence to therapy, a major problem in the care of patients with osteoporosis Includes supplementary material: sn.pub/extras

Inhalt

1. Determinants of peak bone mass acquisition.- 2. Bone mineral assessment of the axial skeleton: technical aspects.- 3. New imaging techniques for bone.- 4. The clinical role of bone density scans in the diagnosis and treatment of osteoporosis.- 5. Biochemical markers of bone turnover basic biochemistry and variability.- 6. Biochemical markers of bone turnover clinical aspects.- 7. Biomechanics of bone.- 8. Mechanical influences on bone mass and morphology.- 9. Exercise in the prevention of osteoporosis-related fractures.- 10. The physiology of and cell biology of calcium transport in relation to the development of osteoporosis.- 11. Calcium, bone, and life.- 12. Basic aspects of Vitamin D nutrition.- 13. Clinical aspects of the use of vitamin D and its metabolites in osteoporosis.- 14. The basic biology of estrogen and bone.- 15. Estrogens and Estrogen Agonists/Antagonists.- 16. Androgen action in bone: basic cellular and molecular aspects.- 17. Androgens actions on bone clinical aspects.- 18. Salmon calcitonin: an update on its clinical utility in osteoporosis.- 19. Bisphosphonate mechanisms of action.- 20. Bisphosphonates treatment of osteoporosis.- 21. Basic aspects of parathyroid hormone in skeletal health.- 22. Clinical use of parathyroid hormone in osteoporosis.- 23. Screening for osteoporosis.- 24. Osteoporosis in men.- 25. Glucocorticoid-induced osteoporosis.- 26. Transplantation osteoporosis.- 27. Treatment compliance and adherence.