Nitrosamine

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Nitrosamines are chemical compounds of the chemical structure R1N(-R2)-N=O, some of which are carcinogenic. Nitrosamines are produced from nitrites and secondary amines, which often occur in the form of proteins. Their formation can occur only under certain conditions, including strongly acidic conditions such as that of the human stomach. High temperatures, as in frying, can also enhance the formation of nitrosamines. These cooking styles may be responsible for thousands of cases of colon cancer per year across the world. The presence of nitrosamines may be identified by the Liebermann''s reaction. Under acidic conditions the nitrite forms nitrous acid (HNO2), which is protonated and splits into the nitrosonium cation N O+ and water: H2NO2+ = H2O + NO+. The nitrosonium cation then reacts with an amine to produce nitrosamine.