Testosterone Therapy for Functional Hypogonadism provides an evidence-based examination of the role of testosterone treatment in men with functional hypogonadism.

Written for healthcare professionals, medical researchers, and readers seeking a deeper understanding of testosterone deficiency, the book explores the complex interplay among testosterone, aging, lifestyle, metabolic health, and chronic disease.

It offers a clinically focused overview of the pathophysiology, clinical presentation, diagnosis, and management of the condition, while critically evaluating the evidence for treatment. Drawing on recent randomized clinical trials, systematic reviews, and meta-analyses, it examines efficacy and safety, patient selection, monitoring, and long-term outcomes. Particular attention is given to metabolic and cardiometabolic health, body composition, sexual function, physical performance, and quality of life, as well as to key areas of ongoing scientific debate.

By integrating research findings with practical clinical considerations, the book provides a framework for informed, individualized patient care and highlights priorities for future research.

Provides clear clinical guidance based on the latest evidence for testosterone therapy for male functional hypogonadism Highlights personalized treatment approaches for different subgroups Incorporates practical case studies to enhance understanding

Autorentext

Dr. Nikolaos Theodorakis, M.D., Ph.D.(c), specializes in lifestyle medicine and cardiometabolic health, with a particular focus on obesity and testosterone therapy. He serves as Scientific Director of Giatros Nutrition Private Medical Practice - Medical P.C., where his work focuses on advancing evidence-based approaches to cardiometabolic medicine and male hormonal health.

Inhalt

Part I: Foundations of Testosterone Replacement Therapy.- 1. Introduction to Functional Hypogonadism.- 2. Physiology of Testosterone and the Hypothalamic-Pituitary-Testicular Axis.- 3. Pathophysiology of Functional Hypogonadism.- Part II: Clinical Evaluation and Diagnosis.- 4. Clinical Presentation and Red Flags.- 5. Diagnostic Tools and Laboratory Evaluation.- 6. Differential Diagnosis.- Part III: Treatment Strategies.- 7. Testosterone Replacement Therapy: An Overview.- 8. Lifestyle Interventions, Supplements and Medications to Increase Endogenous Testosterone Production.- 9. Personalized Approaches in Specific Populations.- Part IV: Monitoring and Long-Term Management.- 10. Testosterone Replacement Therapy Complications and Risks.- 11. Monitoring Therapy Efficacy and Safety.- Part V: Emerging Frontiers.- 12. Future Directions in Testosterone Replacement Therapy.- 13. Integrating Testosterone Replacement Therapy into Clinical Practice.