The Gut-Brain Axis

The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, Second Edition presents the most advances on how the gut microbiome influences central nervous system and brain function introduced in the first edition. The book also describes how environmental influences which affect the microbiota, including, diet, exercise, and early-life, impact on the gut-brain axis.

The second edition contains new chapters on metabolomics and the gut-brain-axis; dietary factors in the maintenance of a healthy brain ; the role of gut microbes in neurodegenerative disorders; the link between exercise and the gut-brain-axis; and infant Nutrition, the microbiome and neurodevelopment. In addition, the second edition presents coverage of mechanisms underlying neurological disease; approaches to investigate the role of the microbiome in brain and behavior, and 'next generation' probiotics and prebiotics.

The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota, Second Edition continues to be the "go-to resource for further exploration of the microbiota.

Autorentext

Niall Hyland is a Senior Lecturer in the Department of Physiology at University College Cork in Ireland and a Funded Investigator at APC Microbiome Ireland. Dr Hyland has over 20 years' experience in gastrointestinal physiology and enteric neuroscience and his fields of interest include enteric physiology and pharmacology, the brain-gut axis, and microbiota-host interactions. He received a BSc (Hons) in Biomedical Sciences from the University of Ulster and PhD in Pharmacology from King's College London. Dr. Hyland was a visiting fellow at the Department of Pharmacology and Experimental Therapeutics, Louisiana State University Medical Center, USA and completed postdoctoral training at the University of Calgary, Canada. He returned to Ireland in 2007. He has represented Ireland on the Steering Committee of the European Society of Neurogastroenterology and Motilty and is an Honorary Fellow of the British Pharmacological Society.

Catherine Stanton is a Senior Principal Research Officer at Teagasc Moorepark Food Research Centre, Moorepark, Fermoy, Ireland, a Research Professor at University College Cork, College of Medicine and Health, and one of the original PI of APC Microbiome Ireland. Her research program addresses development of innovative dairy foods and probiotics that influence human health and the developing gut microbiota in early life. She has led numerous national and international grants, including the coordination of a number EU projects on various aspects of probiotics for human and animal applications. ****

Inhalt

1. Correlating the Gut Microbiome to Health and Disease 2. Importance of the Microbiota in Early Life and Influence on Future Health 3. The microbiome and aging 4. Influence of the Microbiota on the Development and Function of the "Second Brain? The Enteric Nervous System 5. Altering the Gut Microbiome for Cognitive Benefit? 6. Gut Microbiota and Metabolism 7. The Influence of the Gut Microbiota in Psychosis 8. Microbiota-Gut-Brain Axis in Neurodevelopmental Disorders 9. Gut microbes in Parkinson's disease: opportunities for microbial-based therapies 10. Exercise and the Brain-Gut-Axis 11. Global and Epidemiological Perspectives on Diet and Mood 12. Dietary interventions and brain-gut disorders 13. Pediatric Nutrition: Implications for the Developing Microbiota-Gut-Brain Axis 14. Dietary polyphenols to maintain healthier brain measures and cognitive function, as mediated by gut microbiota metabolites 15. Probiotics as Curators of a Healthy Gut Microbiota: Delivering the Solution 16. Germ-Free Animals A Key Tool in Unraveling How the Microbiota Affects the Brain and Behavior 17. Metabolomics and the Gut-Brain-Axis 18. Mining for the next-generation microbiota across the Gut-Brain axis: A case study on the translational success of a Bifidobacterium Longum APC1472 19. Reflection/ Perspective:Reflection on psychobiotics, translation and future perspectives on manipulating the microbiome to modulate the gut-brain-axis