Neurovascular Coupling Methods brings the reader up to date with the current state-of-the-art techniques in measuring blood flow in the brain, with chapters describing different techniques or combinations of techniques, applied to specific species in either healthy or abnormal brains. Opening with a section on techniques in normal somatosensory processing, the detailed volume continues with parts covering techniques in normal visual processing, epilepsy and cerebrovascular diseases, such as ischemia, hemorrhage and spreading depression. As a collection in the popular Neuromethods series, this book contains the kind of thorough description and implementation advice that will lead to successful results in the lab.

Authoritative and practical, Neurovascular Coupling Methods serves as an ideal guide for researchers aiming to further our knowledge of these coupling mechanisms in the hopes of ultimately understanding higher order functions such as language and memory and developing novel brain mapping techniques that can be employed in humans.

Provides a variety of techniques available to examine neurovascular coupling in both health and disease Includes step-by-step detail essential for reproducible results Contains key implementation advice from the experts Includes supplementary material: sn.pub/extras

Inhalt

Simultaneous Functional Magnetic Resonance and Two Dimensional Optical Imaging Spectroscopy.- Neurovascular Coupling Investigated by Simultaneous Optical Coherence Tomography and Electrophysiology.- Studying Adenosine and Cerebral Blood Flow (CBF) Using Pharmacological Methods.- Imaging Vasodynamics in the Awake Mouse Brain with Two-Photon Microscopy.- Neurovascular Coupling in the Deep Brain Using Confocal Fiber-Optic Endomicroscopy.- Non-Invasive Neural Imaging and Tissue Oxygenation in the Visual System.- High-Resolution Wide-Field Optical Imaging of Micro-Vascular Characteristics: From the Neocortex to the Eye.- Optical Intrinsic Signal Imaging for Elucidating Functional Structures in Higher Visual Area.- Closed Cranial Window Applications in the Rat: Studies on Neurovascular Coupling Involving Pial Arterioles and the Glia Limitans.- Multi-Spectral Imaging of Blood Volume, Metabolism, Oximetry and Light Scattering.- Physiological Basis of BOLD fMRI Decreases.- Simultaneous Multi-Wavelength Optical Imaging of Neuronal and Hemodynamic Activity.- Non-Invasive Laser-Induced Photoacoustic Tomography for Functional Imaging.- Neurovascular Coupling in Relation to Cortical Spreading Depression.- Cerebral Blood Flow Imaging with Laser Speckle Contrast Imaging.- Cerebral Monitoring and Surveillance Using High Resolution Functional Optical Imaging.