Nanoparticles in Modern Neurological Treatment" provides a comprehensive exploration of the promising field of nanoparticles and their applications in neurology. The book begins with an introduction, laying the foundation by elucidating the properties and applications of nanoparticles in neurological therapies and diagnostics. The introduction provides an overview of nanoparticles, their properties, and their applications in neurological disorders, discussing the rationale behind using nanoparticles in neurological therapies and diagnostics.

Subsequent chapters delve into specific areas of nanoparticle utilization, exploring how nanoparticles are utilized to overcome the blood-brain barrier and effectively deliver therapeutics to the brain for treating various neurological disorders. Nanoparticle-based imaging techniques for diagnosis and monitoring of neurological disorders are examined, along with targeted therapies for neurodegenerative diseases and brain tumors. Additionally, the modulation of inflammation and neuroprotection facilitated by nanoparticles, particularly relevant in conditions like multiple sclerosis and stroke, is discussed. The potential of nanoparticles as biomarkers for diagnosing and tracking neurological disorders is also investigated. Advanced applications include neuroregeneration and repair facilitated by nanoparticles and the emerging field of theranostics combining therapy and diagnosis using nanoparticles in neurological disorders. Lastly, the promising realm of nanoparticle-mediated gene therapy is explored for precision treatment of neurological conditions.

By consolidating current knowledge and exploring future potentials, this book seeks to contribute to advancements in neurology, ultimately improving patient outcomes and quality of life.

Covers a wide array of applications of nanoparticles in neurology Delves into cutting-edge concepts showcasing the latest advancements in the field The multidisciplinary approach explores nanoparticle applications across various neurological disorders

Autorentext

Dr. Bhagavathi Sundaram Sivamaruthi is a Researcher at Chiang Mai University, Chiang Mai, Thailand. He completed his M.Sc. and Ph.D. in Biotechnology at Alagappa University, Karaikudi, India. He was awarded the Lal Singh Pandhi (Bhatia) Medal, A Plaque of recognition for publishing highly cited papers, and the Golden Elephant Award in 2022. He has published over 160 papers with ~4600 citations (h index: 37 and i10 index: 101). He has published several book chapters and conference proceedings as well. He serves as Associate Editor for neuropharmacology in Frontiers in Pharmacology and Frontiers in Neuroscience. His name has been listed in the Top 2% of scientists in the world since 2021 under pharmacology and pharmacy in the survey conducted by Stanford University. His research topics include pharmaceutical sciences, functional food, applied microbiology, food science and technology, nanotechnology, and fermentation.

Dr. Natarajan Sisubalan, Ph.D. in Botany, is currently working at PG and Research Department of Botany, Pachaiyappa's College, Chennai, India. He served as a Proactive Strategy Researcher at Chiang Mai University, Thailand. With robust expertise in plant tissue culture, nanosciences, and molecular biology, Dr. Sisubalan has made significant contributions to botany. This is reflected in his impressive publication record of 30 works, including book chapters, with a cumulative impact factor exceeding 70 in prestigious journals indexed by Scopus and JCR. Before his current role, Dr. Sisubalan served as an Assistant Professor for three years. He further honed his research skills during a postdoctoral fellowship at Northeast Normal University (NENU) in China. His scholarly contributions include editing a special issue of the journal Plant Gene focusing on "Plant Metabolism and Signaling in Response to Biotic and Abiotic Stresses." In addition to his research, Dr. Sisubalan actively participates as a resource person in national and international seminars and faculty development programs, sharing his knowledge and insights with a broader audience. His commitment to sustainable growth is evident in his ongoing efforts to explore the intricacies of nature, with a particular emphasis on combating global warming through innovative scientific approaches. Dr. Sisubalan remains an influential figure in the scientific community, striving to bridge the gap between research and practical applications that address pressing environmental challenges.

Dr. Periyanaina Kesika is a researcher at Chiang Mai University, Chiang Mai, Thailand. She has published over 100 articles in peer-reviewed Journals and has a Scopus h-index of 24 (as of 11 Sep 2024). She completed her M.Sc. and Ph.D. in Biotechnology at Alagappa University, Karaikudi, Tamil Nadu, India. During her M. Sc., she studied the free radical scavenging capacities of mangrove plants and seaweed (- in vitro evaluation) supported by the Tamil Nadu State Council for Science and Technology (TNSCST), India. And studied the battle of mangrove plants and seaweed extracts against foodborne pathogens (in vitro evaluation). During her Ph. D., she studied the pathogenesis and host responses during infection of Caenorhabditis elegans by Shigella spp. His name has been listed in the Top 2% of scientists in the world under pharmacology and pharmacy in the survey conducted by Stanford University. Her current research focuses on the health-promoting benefits of prebiotic, probiotic-based fermented foods.

Dr. Kokkarachedu Varaprasad is working as an Associate Professor in the Facultad de Ingeniería, Arquitectura y Diseño, Universidad San Sebastián, Concepción, Chile. He received PhD (2011) in biocidal temperature-sensitive hydrogels from the Department of Polymer Science and Technology, India. He worked as an Investigator at the Advanced Polymer Research Center (CIPA). He received 3 International Postdoctoral Fellowships at Creighton University USA, Tshwane University of Technology SA, and Universidad de Concepción, Chile. He developed the bioactivity of hybrid nanomaterials for advanced biomedical applications. He has published over 144 articles, including 2 patents, 3 books, and 33 book chapters, has 44 h-index and more than 7500 citations, and is the recipient of 11 research grants (2 projects ranked as 1st and 4th, respectively. He edited special issues for Journals and was a member of several societies. He guided several students in the nano-bio-materials field. His name has been listed in the Top 2% of scientists in the world under biomaterials, nanoscience, and nanotechnology in a recent survey conducted by Stanford University to recognize. His primary objective is to translate primary nano and polymer technology research results for the next generation of biomedical applications.

Inhalt

Introduction to Nanoparticles in Neurology.- Nanoparticles mediated gene therapy for Neurological disorders.- Nanoparticle Based Imaging Techniques in Neurological Disorders.- Nanoparticles mediated treatment for brain tumors.- Role of Nanoparticles in Neurological Regeneration and Repair.- Nanoparticle-Based Biomarkers for Neurological Disorders.- Nanoparticle-Mediated Therapy for Alzheimer's Diseases.- Curcumin-Loaded Nanoparticles in Neurodegenerative Diseases: Alzheimer's, Parkinson's, and Amyotrophic Lateral Sclerosis.- Gold Nanoparticles in Neurological Therapeutics.- Carbon-Based Nanoparticles for Neural Regeneration.- Lipid-Based Nanoparticles for Neurological Drug Discovery.