This textbook discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how bacteria are becoming resistant to these antibiotics. Appropriate for a one-semester course at either the graduate or advanced undergraduate level, this textbook contains worked examples of (1) experimental procedures and (2) interpreting data.

This book is self-contained and includes all necessary background material Written in accessible language Suitable for a one-semester course on Antibiotics and Development of Resistance to Antibiotics Includes supplementary material: sn.pub/extras

Autorentext
Mrinal Bhattacharjee is an Associate Professor at Long Island University.

Klappentext
This textbook discusses how the various types of antibiotics and related drugs work to cure infections. It also delves into the very serious matter of how bacteria are becoming resistant to antibiotics. Appropriate for a one-semester course at either the graduate or advanced undergraduate level, this textbook contains worked examples of experimental procedures and methods of interpreting data.

Inhalt
Introduction.- Antibiotic resistance development.- Major classes of antibiotics.- Relevant concepts in Biochemistry.- The cell wall as a target.- Mechanism of resistance to B-lactams.- Antibiotic Vancomycin.- Antibiotics that inhibit nucleotide synthesis.- Antibiotics that inhibit DNA synthesis.- Drugs that cause DNA cleavage.- Antibiotics that inhibit RNA synthesis.- Antibiotics that inhibit RNA synthesis.- Antibiotics that disrupt membrane structure.