This book serves as a comprehensive guide to the rapidly evolving field of molecular neuropathology of nervous system tumors, as well as the underlying biology and emerging molecular targeted therapies. Special emphasis is given to already established and emerging molecular diagnostic tests in neuropathology, as well as molecular targeted therapies. The book is organized by clinico-pathologic disease entities, and each chapter is written by a team of experts in their field.

Molecular Pathology of Nervous System Tumors is of great value and utility for physicians and scientists involved with or interested in the up-to-date diagnosis and treatment of patients with brain tumors.

Each chapter written by a team of experts in their field Classic histopathology is integrated with underlying oncogenic signaling pathways and disease mechanisms A comprehensive guide to the rapidly evolving field

Inhalt

1. Hereditary Predisposition to Primary CNS Tumors.- 2. Brain Tumor Stem Cells.- 3. Molecular Pathology Techniques.- 4. Low-grade Gliomas.- 5. Ependymoma.- 6. Adult High Grade (Diffuse) Glioma.- 7. High-Grade Gliomas and DIPG (Pediatric).- 8. Oligodendroglial Tumors: Current Treatments and the Promise of Molecular Genetics.- 9. Molecular Pathology of Nervous System Tumors: Medulloblastoma and CNS Primitive Neuroectodermal Tumors.- 10. Subependymal Giant Cell Astrocytoma.- 11. Germ Cell Tumors.- 12. Choroid Plexus Tumors.- 13. Atypical Teratoid Rhabdoid Tumors.- 14. Hemangioblastoma.- 15. Schwannomas.- 16. Molecular Pathology of Nervous System Tumors.- 17. Molecular Genetic Pathology of Meningiomas.