Molecular Pathology of Gynecologic Cancer

Molecular Pathology of Gynecologic Cancer focuses on putting successful molecular strategies into practice for the treatment of gynecologic cancer. The volume begins with an explication of the editors' hypothesis that cancer is mainly a disease of the cell cycle, based on the deregulation of the physiological process of cell reproduction. The following eleven chapters focus on specific issues in gynecologic cancers, including: a proposed model of ovarian serous carcinogenesis, molecular markers for ovarian epithelial cancer, an overview of the pathology of endometrial cancer, molecular genetic aspects of endometrial carcinoma and cervical cancer, a natural history of Human Papilloma Virus (HPV) as it relates to cervical cancer, and hereditary issues in gynecologic cancers. The concluding chapter proposes and outlines a holistic approach to the treatment of female cancer patients. This new volume in Humana's Current Clinical Oncology™ series will be necessary reading for clinicians and experimental researchers alike.

Approaches research into the pathology and treatment of gynecologic oncology from both clinical and experimental perspectives Summarizes studies that have correlated screening, diagnosis, and prognosis with structure and expression profiles of molecular markers Presents new insights made possible by the introduction of advanced technologies into the field Describes the strong association between infection with specific subtypes of HPV and cervical cancer

Inhalt
The Cell Cycle and the Molecular Biology of Cancer.- Ovarian Cancer.- Ovarian Serous CarcinogenesisA Proposed Model.- Molecular Markers in Epithelial Ovarian Cancer.- Endometrial Cancer.- to Endometrial Cancer.- Endometrial Carcinogenesis.- Endometrial CarcinomaMolecular Genetic Aspects.- Cervical Cancer.- Natural History of HPV Infection in Adolescents and Relationship to Cervical Cancer.- Molecular Genetics of Cervical Cancer.- Prevention and Treatment of Cervical Cancer by Vaccination.- Gestational Trophoblastic Disease.- Pathogenesis of Gestational Trophoblastic Lesions.- Hereditary Issues in Gynecological Cancer.- Hereditary Issues In Ovarian Cancer.- Hereditary Factors in Endometrial Cancer.- The Multidisciplinary Therapeutic Approach to Gynecological Cancer in the New Millenium.- The Holistic Approach to Female Cancer Patients.