Investigations of Cellular and Molecular Biophysical Properties by Atomic Force Microscopy Nanorobotics

Awarded as an Outstanding PhD thesis by the Chinese Academy of Sciences in 2015

Describes a comprehensive study on using atomic force microscopy (AFM) to investigate single-cell and single-molecule activities

Explores the biomedical applications of atomic force microscopy (AFM) in clinical practice for targeted cancer therapy

Awarded as an Outstanding PhD thesis by the Chinese Academy of Sciences in 2015 Describes a comprehensive study on using atomic force microscopy (AFM) to investigate single-cell and single-molecule activities Explores the biomedical applications of atomic force microscopy (AFM) in clinical practice for targeted cancer therapy Includes supplementary material: sn.pub/extras

Autorentext
Dr. Mi Li received his B.E. and M.E. degree from Huazhong University of Science and Technology, Wuhan, China in 2006 and 2008, respectively, and Ph. D. degree from Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang, China in 2015. Currently Dr. Li is Associate Professor at the Shenyang Institute of Automation and his research areas include micro/nano automation technology, atomic force microscopy, nanorobot and cell mechanics. He has published more than 30 articles in academic journals as first author, and received Outstanding Doctoral Dissertation Award of Chinese Academy of Sciences in 2016.

Inhalt
Introduction.- Immobilization methods for observing living cells.- Label-free measuring the mechanics of single cells.- Single-molecule recognition and force measurements.- Mapping membrane proteins on cell surface.- Applications of single-cell and single-molecule physiological properties characterization methods in clinical lymphoma treatment.- Conclusion.