Discussing the diagnosis, therapy and prognosis in one self-contained text, this volume presents a broad view of the CNS tumor and brain tumor imaging fields of research in Europe. The genetics of malignant brain tumors and gene amplification are explained, as well as standard and new imaging modalities.

This eighth volume in the series Methods of Cancer Diagnosis, Therapy, and Prognosis discusses in detail the classification of the CNS tumors as well as brain tumor imaging. Scientists and Clinicians have contributed state of the art chapters on their respective areas of expertise, providing the reader a whole field view of the CNS tumors and brain tumor imaging in Europe. This fully illustrated volume: Explains the genetics of malignant brain tumors and gene amplification using quantitative-PCR; Presents a large number of standard and new imaging modalities, including magnetic resonance imaging, functional magnetic resonance imaging, diffusion tensor imaging, amide proton transfer imaging, positron emission tomography, single photon emission computed tomography, magnetic resonance single voxel spectroscopy and intraoperative ultrasound imaging, for staging and diagnosing various primary and secondary brain cancers; Explains the usefulness of imaging methods for planning and monitoring (assessment) therapy for cancers; Discusses diagnosis and treatment of primary CNS lymphomas, CNS atypical teratoid/rhabdoid and CNS Rosai-Dorfman disease; Includes the subject of translational medicine. Professor Hayat has summarized the problems associated with the complexities of research publications and has been successful in editing a must-read volume for oncologists, cancer researchers, medical teachers and students of cancer biology.

The only book that discusses cancer diagnosis, therapy, and prognosis together in one volume Discusses the molecular processes that lead to the development and proliferation of cancer cells Includes recent major advances in cancer diagnosis and therapy assessment The text is supported throughout with illustrations The information in the book identifies patients with high likelihood of clinical benefits from a specific treatment Includes supplementary material: sn.pub/extras

Inhalt

1. The World Health Organization Classification of the Central Nervous System Tumors: an Update Using Imaging; 2. Brain Tumor Imaging: European Association of Nuclear Medicine Procedure Guidelines; 3. Assessment of Heterogeneity in Malignant Brain Tumors; 4. Diagnosing and Grading of Brain Tumors: Immunohistochemistry; 5. Malignant Brain Tumors: Roles of Aquaporins; 6. Brain Metastases: Gene Amplification Using Quantitative Real-time Polymerase Chain Reaction Analysis; 7. Cyclic Amp Phosphodiesterase-4 in Brain Tumor Biology: Immunochemical Analysis; 8. Radiosurgical Treatment of Progressive Malignant Brain Tumors; 9. Anti-Vascular Therapy for Brain Tumors; 10. Glial Brain Tumors: Antiangiogenic Therapy; 11. Brain Tumors: Amide Proton Transfer Imaging; 12. Diffusion Tensor Imaging in Rat Models of Invasive Brain Tumors; 13. Brain Tumors: Diffusion Imaging and Diffusion Tensor Imaging; 14. Brain Tumors: Planning and Monitoring Therapy with Positron Emission Tomography; 15. Clinical Evaluation of Primary Brain Tumor: O-(2-[18F]Fluorethyl)-L-Tyrosine Positron Emission Tomography; 16. Combined use of [F-18]Fluorodeoxyglucose and [C-11]Methionine in 45 PET-Guided Stereotactic Brain Biopsies; 17. Hemorrhagic Brain Neoplasm: 99MTc-Methoxyisobutyl Isonitrile-Single Photon Emission Computed Tomography; 18. Brain Tumor Imaging Using p-[123I]IODO-L-Phenylalanine and SPECT; 19. Diagnosis and Staging of Brain Tumors: 20. Parallel Magnetic Resonance Imaging Acquisition and Reconstruction: Application to Functional and Spectroscopic Imaging in Human Brain; 21. Intra-Axial Brain Tumors: Diagnostic Magnetic Resonance Imaging; 22. Brain Tumors: Apparent Diffusion Coefficient at Magnetic Resonance Imaging; 23. Magnetic Resonance Imaging of Brain Tumors Using Iron Oxide Nanoparticles; 24. Metastatic Solitary Malignant Brain Tumor: Magnetic Resonance Imaging; 25. Brain Tumor Resection: Intraoperative Ultrasound Images; 26. Primary Central Nervous System Lymphomas: Salvage Treatment; 27.Central Nervous System Atypical Teratoid/Rhabdoid Tumors: Role of Insulin-Like Growth Factor I Receptor; 28. Central Nervous System Rosai-Dorfman Disease.