This book presents a comparison analysis of two cancer treatment therapies: carbon ion therapy and protontherapy. It is divided in 5 sections. The first ones gives the reader a brief history of Radiotherapy and types of radiation. In the second section, the techniques and equipments, including new ones in development such as Cyclinac , Laser and DWA, are described. The third section describes biophysical (such as stopping power and LET) and biological (such as RBE and OER) properties, the fundamental experiments and clinical area. The fourth section presents models and the fifth section compares both techniques, showing advantages and disadvantages of each, and their similarities.

Presents a comparative analysis of two cancer treatments based on ion therapy Describes new equipments in development such as Cyclinac , Laser and DWA Special chapter on clinical experiences using the techniques Includes supplementary material: sn.pub/extras

Autorentext

Marcos d'Avila Nunes is an Associate Professor (MS-5) at the University of São Paulo (USP) and graduated from the Faculty of Medicine of Ribeirão Preto/USP in 1967. He did his postgraduate studies in Advanced Theoretical Physics at the School of Engineering of São Carlos/USP from 1968-69. He received his PhD in 1972 and became Full Professor in the Biomedical Sciences Institute at USP in 1977. He did post doctorate research at the Massachusetts Institute of Technology (1974-75), Boston University Medical Center (1974-75), National Institutes of Health (1976), American National Red Cross (1976), University of South Carolina (1981-82) and Wayne State University (1982). Prof. Nunes is known worldwide for his electrophysiological studies in biological membranes, the application of thermodynamics of irreversible processes in membranes and also by the development of electron paramagnetic resonance (EPR) to study the behavior of molecular components of the biological membranes, subjected to a drop / rise in temperature and their simulations. Prof. Nunes has published his work in Medical Informatics and participated in National and International Congresses as chairman of Molecular Biophysics. He is the author of a book in advanced physics "Large Hadron Collider: New Era of Discoveries" and he is responsible for seven post graduation courses at USP.

Inhalt

Introduction.- Equipments and Techniques.- Physical and Biological Rationale for using Ions in Therapy.- Modelling Heavy Ion Radiation Effects.- Clinical Experiences with C-Ion Therapy.- Appendix.