Manual of Childhood Infections

Autorentext

Professor Penelope Bryant (MA BM BCh MRCP MRCPCH FRACP PhD) is a paediatric infectious diseases physician who trained in Oxford and London, UK, and now practises in Infectious Diseases and Hospital-in-the-Home at The Royal Children's Hospital Melbourne, Australia. She did a PhD at the University of Melbourne, and combines research interests there and at the Murdoch Children's Research Institute, in improving antibiotic use in children, preventing antimicrobial resistance and impacting both by managing children out of hospital. A/Prof Bryant has led multicentre randomised trials and impacted paediatric clinical care nationally and internationally. She has won awards for her pioneering work in Hospital-in-the-Home and mentorship of junior researchers. Professor Mark Cotton (MB ChB; M.Med (Paed) FCPaed (SA) PhD DCH (SA) DTM&H) is an emeritus professor at Stellenbosch University. He trained in Paediatric Infectious Diseases in Denver, CO between 1991 and 1994. He established and led the Family Centre for Research with Ubuntu (FAMCRU) between 2001 and 2021 for clinical trials. He conducted several pivotal paediatric clinical trials, including antiretroviral strategy and isoniazid prophylaxis. He has had leadership positions in WSPID since 2013. He is editor-in-chief of the Southern African Journal of Infectious Diseases and has published over 400 papers.

Klappentext

Trusted by paediatricians around the world, the Manual of Childhood Infections, also known as the Blue Book, returns in a fully updated fifth edition. This essential handbook brings together global expertise to deliver fast, reliable answers for anyone caring for children with infectious diseases. Written by specialists from all WHO regions, it reflects real-world practice across diverse settings, including guidance tailored to resource-limited settings.

With 130 concise, clinically focused chapters, the handbook offers an evidence-based approach to every major childhood infection. Each chapter provides at-a-glance support for busy clinicians broken down into global epidemiology, transmission and incubation periods, typical and atypical presentations, diagnosis, management, antimicrobial and supportive care, outcomes, prevention, 'what's new', and 'what's next', all in a clear bullet-point format designed for rapid consultation.

Covering everything from common infections to emerging threats and neglected tropical diseases, this edition equips healthcare professionals with the knowledge they need to deliver safe, effective care anywhere in the world and remains the indispensable companion for clinicians treating infants, children, and adolescents with infectious diseases.

Inhalt

• Section 1 - Antimicrobial treatment of infections
• 1: Shalom Ben-Shimol, Ron Dagan Julie Copelyn: Antibacterials
• 2: Gary Reubenson, Patricia Saltigeral: Antivirals
• 3: Charalampos Antachopoulos, Joseph Meletiadis: Antifungals
• 4: Roland van Rensburg: Antiparasitics
• 5: Andrew Whitelaw, Phoebe Williams, Shirani Chandrasiri, Solomie Deribessa: Antimicrobial resistance
• 6: Theo Zaoutis, Penelope Bryant, Solomie Deribessa: Antimicrobial stewardship
• 7: Devika Dixit, Kaman Cheung, Bello Oluwaseun, Penelope Bryant: Optimising antimicrobials for children
• Section 2 - Prevention of infections
• 8: Nicolette du Plessis, Beckie Tagbo, Adaobi Bisi-Onyemachi, Dr Azubuike Nwako: Childhood immunisations
• 9: Charles Wiysonge, Margie Danchin, Jessica Kaufman, Aisha Muhammad Jibril: Vaccine hesitancy
• 10: Brian Eley, Denisse Vaquera: Immunisation in immuncompromised children
• 11: Angela Dramowski, Louisa Erasmus, Spyros Karageorgos: Infection prevention and control in hospital and community
• 12: Shamez Ladhani, Phoebe Williams, Nilushi de Silva: Emerging infections and pandemic preparedness
• 13: Emma Goeman, Meryta May, Mohammad Issack, Dimitri van der Linden, Olivier Van den Berg, Marie Hallin, Michelle Sam: Laboratory diagnosis of infection
• Section 3 - Infections in particular groups
• 14: Saurav Basu, Adolfine Hokororo, Indi Trehan, Aashima Dabas, Raul Copana: Approach to infection management in resource-limited settings
• 15: Sithembiso C. Velaphi, Paul Heath, Stefania Vergnano, Reenu Thomas, Khuen Ng: Neonatal infections
• 16: Thomas Lehrnbecher, Gabrielle Haeusler, Sam Bannister, Laila Al Yazidi: Immunocompromised children
• 17: Mutsa Bakwura-Darangembizi, Raul Copana, Eduardo Suarez: Infections in malnourished children
• 18: Koen Vanden Driessche: Children with cystic fibrosis/bronchiectasis
• 19: Andrew Riordan, Matthew Ellis, Jane Wilson Howarth, Tanya Rogo, WIll Wong: Children visiting and arriving from other countries to high income settings
• 20: Paula Vaz, David Elliman: Children who are refugees or in disasters in resource-limited settings
• Section 4 - Clinical infection presentations
• Broad presentation
• 21: Marieke Emonts, Elisabetta Ghimenton: Sepsis
• 22: Tom Wolfs, Lieke de Vankrijker: Toxic shock syndrome
• 23: Angela Dramowski,Khalfan Alabdali: Central-line-associated bloodstream infection
• 24: Nicole van de Kar, Kioa Wijnsma: Haemolytic uraemic syndrome
• 25: Gill Sorour, Suvaporn Anugulruengkitt, Usa Thisyakorn: Rash
• 26: Anita Modi, Pui-Ying Iroh Tam: Pyrexia of unknown origin
• 27: Athimalaipet Ramanan, Marion Roderick, Praisoody Sinnappurajar: Periodic fever
• 28: Asha Bowen, Liesl Zuhlke, Hazel Dobinson: Rheumatic fever
• 29: Dave Burgner, Linny Phuong: Kawasaki disease
• 30: Kirsty Le Doare, Andres Alarcon: Congenital infection
• 31: Austen Worth, Paul Torpiano: Recurrent or unusual infections
• 32: Ian Maconochie, Stephen Novak, Ayobami Oyetunji Alabi: Animal bites, burns and trauma infections
• 33: Shaun Barnabas: Post-infectious chronic fatigue syndrome
• Organ-specific presentation
• 34: Andrew Pollard, Manish Sadarangani: Meningitis
• 35: Philip Britton, Mike Starr: Encephalitis and myelitis
• 36: Tinsae Alemayehu, Paola Villaneuva, Kelly Márquez Herrera: Brain abscess/empyema/VP shunt infection
• 37: Parvathi Kumar, Andres Alacorn: Conjunctivitis
• 38: Derrick Smit, David Meyer: Ocular infections
• 39: James Loock, Marc Merven, Shaun Adam; Kathryne Wright, Rachel Blokland, Helen Muirhead, Siobhan Oelofsen, Ann Thomas: Ear and mastoid infection
• 40: Jolanta Bernatoniene, Hayley King: Lymphadenopathy
• 41: Ulrich Heininger, Finn Ryan: Upper respiratory tract infection
• 42: Lilly Verhagen, Adegoke Falade: Lower respiratory tract infection
• 43: John Lawrenson, Barend Fourie: Cardiac infections - endocarditis/myocarditis/pericarditis
• 44: Jim Buttery, Miguel O'Ryan, Rachael Purcell: Gastroenteritis
• 45: Helena Rabie, Penelope Rose: Intra-abdominal infection/Peritonitis (including liver abscess)
• 46: Roberto Santos, Annaleise Howard-Jones, Penelope Bryant: Urinary tract infection
• 47: Theresa Barton, Katja Doerholt, Noppadol Wacharachaisurapol: Sexually-transmitted infection
• 48: Saul Faust, Daniel Jarovsky: Bone and joint infection
• 49: Cilian O Maoldomhnaigh, Laila Ibrahim, Penelope Bryant: Skin and soft tissue infection
• 50: David Foley, Phillipa Edmiston: Surgical site infections
• Section 5 - Specific pathogens or groups of pathogens
• 51: Nicola Principi, Susanna: Adenovirus
• 52: Frank Zhang, Robyn Slicock: Amoebiasis
• 53: Ming Chen, Celia Cooper: Anaerobic infections
• 54: Phillip Britton, David Pham, Laila Al-Yazidi: Arthropod-borne viruses
• 55: Dan Yeoh, Brendan McMullan, Michael-John Fay: Aspergillosis and other moulds
• 56: Nicola Principi, Susanna Esposito, Marta Palusi?ska-Szysz, Bo?ena Kowalczyk, Annemarie van Rossum, Patrick M. Meyer Sauteur: Atypical pneumonia (Mycoplasma, Chlamydia and Legionella)
• 57: Robert Cunney: Botulism
• 58: Julia Kenny, Hanna Schmid: Brucellosis
• …