Autorentext

Dr Mahmood Ahmed is an Assistant Professor of Chemistry, Department of Chemistry, Division of Science and Technology, University of Education, College Road, Lahore-Pakistan. He received his M.Sc. (January, 2003), M.Phil. (July, 2013) and PhD (March, 2018) degrees in Chemistry from Institute of Chemistry, University of the Punjab, Lahore-Pakistan. He has more than 20 years of professional, research and teaching experience. He has published 100 research/review articles as author/co-author in national and international peer reviewed journals, resulted in 1502 citations, impact factor = 177.752, h-index = 20 and i10-index = 41. He has reviewed 456 research articles for 67 international journals and handled 20 articles as an editor. He has also supervised/co-supervised 9 MS students in this field so far. Moreover, 16 of his abstracts published in proceedings of national and international conferences.

Dr Syed Salman Shafqat is serving as an assistant professor of chemistry at the University of Education, Lahore. He accomplished his doctorate degree on prestigious from Malaysia. He completed his doctoral degree research work under the auspices of Prof. Dr. Amir Khan and the dissertation entitled Synthesis and Characterization of Silica Nanoparticles Grafted with Selected Heterocyclic Derivatives. He has published thirty five publications on International peer-reviewed Journals as well as several book chapters and his publications impact factor is more than 100.

Klappentext

Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin is a comprehensive reference on techniques to enhance the bioavailability of curcumin, while also covering sustainability aspects across its production cycle. This book focuses on the information needs of pharmaceutical scientists aiming at developing drug delivery systems and formulations that can maximize the therapeutic impact of curcumin drugs. After an introduction to curcumin therapeutic properties, the authors delve into the bioavailability challenges confronted by curcumin, discussing influencing factors, pharmacokinetic pathways, and formulations to augment its bioaccessibility. Chapter 3 explores innovative formulation paradigms, encompassing nanoparticle-based delivery systems and lipidic matrices, tailored to overcome solubility limitations and increase absorptive efficacy. Chapter 4 covers delivery systems, encompassing prodrug strategies, encapsulation modalities, and nanocarrier technologies. Chapter 5 investigates sustainable sourcing and production, raising awareness to ethical cultivation practices, eco-friendly extraction methodologies, and proficient waste management techniques within curcumin production processes. In Chapter 6 discusses balancing bioavailability augmentation with sustainability principles including case studies. Chapter 7 navigates the domain of pharmacokinetic studies and clinical trials, providing an overview of bioaccessibility and bioavailable formulations. Chapter 8 explores safety profiles, regulatory requirements, and quality benchmarks, encompassing product labeling and claims concerning curcumin's bioavailability and sustainability. Chapter 9 casts a future view contemplating nascent technologies for bioavailability and sustainability optimization. The final chapter concludes the book with the author's observations on its central themes. Curcumin Bioavailability and Sustainability as Therapeutic Agent: Strategies for Sustained Release Curcumin provides practical strategies to be explored by pharmaceutical scientists in increasing bioavailability of curcumin formulations. Research physicians and nutritionists may also benefit from the evidence-based information on curcumin's therapeutic activities provided across the book.

Inhalt

1. Introduction to Curcumin as a Therapeutic Agent
   
   2. Bioavailability Challenges of Curcumin
   3. Formulation Approaches for Enhancing Curcumin Bioavailability
   4. Novel Delivery Systems for Curcumin
   5. Sustainable Sourcing and Production of Curcumin
   6. Bioavailability and Sustainability Considerations in Formulation Development
   7. Pharmacokinetic Studies and Clinical Trials
   8. Safety and Regulatory Considerations
   9. Future Directions and Challenges
   10. Conclusion and Closing Remarks