This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate and postgraduate students fascinating insights into genes and their regulation in eukaryotes and higher organisms.

Comprehensive and detailed purview of long non coding RNAs from unicellular to multicellular organisms Includes a special section on the emerging field of IncRNAs in brain development Includes a detailed chapter on the role of IncRNAs in cancer and their therapeutic potential Includes supplementary material: sn.pub/extras

Autorentext
Prof. M.R.S. Rao is one of the most prominent scientists in India, currently working as honorary professor at Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India. In 2010 he received the country's 4 th highest civilian award "PadmaShri" from the Government of India for his outstanding contribution to the field of bio-medical sciences.

Prof. Rao obtained his PhD from the Indian Institute of Science, Bangalore in 1973 and subsequently worked in different capacities at various renowned international institutes/universities such as Baylor College of Medicine, USA, Harvard Medical School, USA, and Ludwig Institute for Cancer Research, University of California at San Diego, USA,. His area of interest spans RNA biology, molecular and cellular biology, genomics and cancer biology, molecular genetics of type II diabetes & cancer genetics, and chromatin biology. He has made seminal contribution in delineation of the biology and role of long non-coding RNA molecules.

He has published over 150 articles in respected national and international journals and is a member of various prestigious national and international societies/associations. He has received numerous national and international awards during his distinguished scientific career.

Inhalt

Chapter 1. Non coding RNA: History, Discovery and Classification of non coding RNA.- Chapter 2. Long non coding RNA: Genome organization and mechanism of action.- 3. Long non coding RNAs in Invertebrates: Drosophila.- Chapter 4. Long non coding RNAs in unicellular organisms: Yeast.- Chapter 5. Long non coding RNAs in Plants.- Chapter 6. Long non coding RNAs in mammalian development and disorders.- Chapter 7. Long non coding RNAs in Cancer and therapeutic potential.- Chapter 8. L ong non coding RNAs in Stem cell and Differentiation.- Chapter 9. Long non coding RNAs in Brain development.- Chapter 10. Technological developments in lncRNA Biology.