an up-to-date overview of the technique for trapping and manipulation of micro and nanoparticles with light, sound, temperature gradients and electric fields.

Autorentext

*Lin Feng received the Ph.D. degree in Micro/Nano Systems from Nagoya University, Japan, in 2014. He is currently a Professor with the School of Mechanical Engineering and Automation, Beihang University. His current research focuses on optoelectronic tweezer-based micro/nano control systems, intelligent microrobots, and biomanufacturing, with applications in cancer targeted therapy, tissue engineering, and regenerative medicine. **Menglu Tan is a postdoctoral fellow in the School of Mechanical Engineering and Automation at Beihang University. She received her Ph.D. at the Shanghai Institute of Applied Physics, Chinese Academy of Sciences in 2022. Her current research focuses on deep learning applied to optoelectronic tweezer images and medical imaging.Ao Wang received his Ph.D. degree from the School of Mechanical Engineering and Automation, Beihang University. His research mainly focuses on optoelectronic tweezer-based micro/nano manipulation and the interaction mechanisms between particles under multi-physical field coupling.Jiaying Zhang* is a Chief Technician at the Institute of Medical Innovation and Research, Peking University Third Hospital. She earned Ph.D. in synthetic biology from Tsinghua University in 2020, and later completed postdoctoral research in the School of Mechanical Engineering and Automation at Beihang University. Her present research is centered on the development of small nucleic acid drugs for targeted tumor therapy.

Klappentext

Overview of a technique for trapping and manipulation of micro and nanoparticles with light, sound, temperature gradients, and electric fields Optoelectronic Tweezers for Manipulation at the Micro and Nano Scale takes readers on a journey to explore the fascinating world of Optoelectronic Tweezers (OET) and their applications in micro- and nano-scale manipulation. Starting from the evolution of nanotechnology, this book delves into the development of optical micromanipulation technologies such as Optical Tweezers (OT) and the emergence of OET as a cutting-edge technology with superior performance in various aspects. The fundamental principles of OET, its significance, and diverse applications across different fields are meticulously examined. This book covers the working mechanisms, operational principles, optical foundations, photovoltaic effects, and material selection processes in OET technology. Detailed insights into the components of OET devices, including standard OET and photovoltaic OET, are provided, along with a comprehensive analysis of manipulation forces and dielectrophoretic effects within OET chips. Written by a highly qualified researcher and author in the field, Optoelectronic Tweezers for Manipulation at the Micro and Nano Scale includes information on:

• Practical applications of OET in biomedical fields, showcasing its efficacy in cell sorting, trapping, lysis, patterning, immunoreaction analysis, DNA transfection, and other crucial biological processes
• Versatility of OET in manipulating a myriad of micro and nano objects, ranging from living organisms like cells and bacteria to non-living entities such as nanoparticles and microspheres
• Integration of OET with complementary technologies like microfluidics, photocuring, electrowetting, and image recognition

• Interplay of optical principles, light sources, and photovoltaic mechanisms in OET setups Providing deep knowledge into the boundless opportunities offered by OET technology, Optoelectronic Tweezers for Manipulation at the Micro and Nano Scale is an excellent reference on the subject for materials scientists, thermodynamics physicists, and laser specialists, along with all professionals in the optical industry.

  Inhalt

  1. INTRODUCTION
     1.1 History Background and Brief Overview
     1.2 Importance and Applications in Various Fields

  2. FUNDAMENTALS OF OPTOELECTRONIC TWEEZERS
     2.1 Types of OET Device
     2.2 Working Mechanisms
     2.3 Finite Element Simulation Analysis

  3. OPTICS AND LIGHT SOURCE
     3.1 Optics Involved in Optoelectronic Tweezers
     3.2 Light Source and Characteristics

  4. ELECTRO-OPTICAL INTERACTIONS
     4.1 Interaction between Light and Electric Field
     4.2 Selection and Preparation of Photoelectric Materials

  5. EXPERIMENTAL TECHNIQUES AND SETUPS
     5.1 Overview of Experimental Setup
     5.2 Detailed Description of the Optoelectronic Tweezer Device
     5.3 Advanced OET Product Introduction
     5.4 Common Challenges and Solutions

  6. APPLICATIONS IN BIOLOGYY
     6.1 Manipulation of Biological Entities
     6.2 Biomedical Applications and Advancements

  7. APPLICATIONS IN PHYSICS AND MATERIALS SCIENCE
     7.1 Manipulation of Micro Particles
     7.2 Manipulation of Nano Particles
     7.3 Manipulation of Droplet
     7.4 Manipulation of Micromachines

  8. INTEGRATION WITH OTHER TECHNOLOGIES
     8.1 Integration with Microfluidics
     8.2 Photocuring Technology
     8.3 Electrowetting Technology
     8.4 Image Recognition

  9. CASE STUDIES AND EXPERIMENTS
     9.1 In-Depth Analysis of Notable Experiments
     9.2 Case Studies Showcasing Diverse Applications

  10. CHALLENGES AND FUTURE DIRECTIONS
      10.1 Current Challenges
      10.2 Innovation and Ongoing Research
      10.3 Future Development Direction and Suggestions