Autorentext

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Inhalt
Section 1: Historical Perspective.- 1 alpha-2 Adrenergic Receptors: A Historical Perspective.- Section 2: Characterization of the Receptor and its Binding Site.- 2 Biochemistry of alpha-2 Adrenergic Receptors.- Section 3: Biochemical Mechanisms of Receptor Action.- 3 Mechanisms for Inhibition of Adenylate Cyclase by alpha-2 Adrenergic Receptors.- Section 4: Correlation of Receptor Binding and Function.- 4 StructureActivity Relationships for alpha-2 Adrenergic Receptor Agonists and Antagonists.- 5 Functions Mediated by alpha-2 Adrenergic Receptors.- Section 5: Receptor Regulation.- 6 Regulation of alpha-2 Adrenergic Receptors.- Section 6: Future Vistas.- 7 What Happens Next? A Hypothesis Linking the Biochemical and Electrophysiological Sequelae of alpha-2 Adrenergic Receptor Occupancy with the Diverse Receptor-Mediated Physiological Effects.