This book focuses on bioinformatics, the study of the management and analysis of information used in biological systems. Particular emphasis explains to the reader how to study and extract useful information, such as relatedness of species, function of specific sequences, and genome organization from genomic sequences.

This book focuses on the algorithmic aspects of bioinformatics and not on databases and software packages. There are two important discriminating characteristics that sets the book apart. It connects the algorithmic aspects and approaches to bioinformatics with the biological context while maintaining a user friendly and accessible description of the algorithms. The authors have curated the content for use a stand alone reference or the book will fit a one semester course on the subject.

Introduces and defines the foundation of bioinformatics in relation to biology Emphasizes the algorithmic aspects of bioinformatics Focuses on extraction of information on relatedness of species, function of sequences, and genome organization

Autorentext

Khalid Sayood received the B.S. and M.S. degrees in electrical engineeringfrom the University of Rochester, Rochester, NY, in 1977 and 1979, respectively, and the Ph.D. degree in electrical engineering from Texas A&M University, College Station, in 1982. From 1995 to 1996, he served as the Founding Head of the Computer Vision and Image Processing Group at the Turkish National Research Council Informatics Institute. From 1996 to 1997, he served as a Visiting Professor at Böaziçi University, Istanbul, Turkey. He served on the faculty of the Department of Electrical and Computer Engineering at the University of Nebraska - Lincoln, from 1982 to 2024. He is currently an Emeritus Professor in the Department. He is also a partner at Nebraska R&D. He is the author of Introduction to Data Compression, 5th ed. (Morgan Kaufmann, 2017), Understanding Circuits: Learning Problem Solving Using Circuit Analysis (Morgan Claypool, 2005), and Learning Programming Using MATLAB (Morgan Claypool, 2006), Joint Source Channel Coding Using Arithmetic Codes (Morgan Claypool, 2010), Computational Genomic Signatures (Morgan Claypool, 2011), Signals and Systems: A one semester course (Springer 2021), Bioinformatics: A one semester course (Springer 2023), and the Editor of Lossless Compression Handbook (Academic Press, 2002). His research interests include bioinformatics, data compression, and biological signal processing.

Inhalt
Introduction.- Molecular Biology Primer.- A bit of Biology.- Pairwise Sequence Alignment.- Multiple Sequence Alignment.- Molecular Phylogeny.