Autorentext
Dr. Kanwal Rehman is working as an Associate Professor at the Department of Pharmacy in The Women University, Multan, Pakistan. Dr. Rehman received her PhD in Pharmacology from Zhejiang University, China. She nurtures
a keen interest in the pathogenesis of metabolic disorders and new therapeutic modalities for its treatment. Currently, she
is focusing on the investigation of the role of pharmacogenomics based upon gene polymorphism on various molecular and
metabolic pathways that are involved in mitogenic disorders and treatment strategies, like natural biogenic compounds against different risk factors of metabolic disorders, including pancreatitis, cardiometabolic disorders, and hormonal imbalance. Dr. Rehman has also been awarded the Research Productivity Award by the Pakistan Council for Science and Technology, Pakistan; the PAS Gold Medal from the Pakistan Academy of Sciences; and the A.R. Shakoori Gold Medal from the Zoological Society of Pakistan. Dr. Akash is currently working as an Associate Professor at the Department of Pharmaceutical Chemistry, Government College University Faisalabad, Pakistan. He got his PhD degree in Pharmaceutical Analysis from Zhejiang University, China. Currently, he is focusing on investigating the effect of endocrine disrupting
chemicals on various molecular and metabolic pathways that are involved in metabolic disorders and their treatment strategies. His research work is cutting-edge and worthy of extension in developing countries, like Pakistan, where it can be most beneficial and cost-effective, especially for diabetic patients. Based on his significant scientific contributions in
the field of Pharmaceutical Sciences, he has been awarded Research Productivity Awards” from the Pakistan Council for Science and Technology, the PAS Gold Medal from the Pakistan Academy of Sciences, and the A.R. Shakoori Gold Medal from the Zoological Society of Pakistan.

Klappentext
Biochemical and Molecular Mechanisms of Secondary Metabolites in Metabolic Diseases explores the therapeutic potential and pharmacological roles of secondary metabolites (SMs) in managing metabolic disorders. This comprehensive volume provides a detailed examination of the biochemical pathways, molecular mechanisms, and pharmacodynamics of SMs, offering insights into their potential as future drug candidates for metabolic diseases. The book begins by explaining the differences between secondary and primary metabolites, providing clear classification and organization of SMs. It highlights recent research on SMs, including receptor interactions and molecular signal transduction pathways, to showcase their potential as interventions against metabolic disorders.

The role and mechanistic details of SMs at the molecular level are illustrated, emphasizing their pharmacological participation in treating conditions such as obesity, diabetes, cardiovascular diseases, and inflammation. This book is an essential resource for students and professionals in pharmacy, medical subjects, nursing, herbal medicine, and traditional medicine programs, aligning with curricula in medical ethnobotany, ethnopharmacology, pharmacognosy, phytochemistry, and related fields. It also serves as a valuable reference for researchers in pharmacology, biochemistry, and medicinal chemistry, as well as clinicians interested in natural product-based therapeutics for managing metabolic conditions.

Inhalt

1. Introduction of Secondary Metabolites as Bioactive Compounds in Health
   
   2. Sources and Extraction Techniques for Secondary Metabolites
   3. Secondary Metabolites in Therapeutics: Biochemical and Pharmacological Perspectives
   4. Anti-Obesity Effects of Secondary Metabolites: Molecular Mechanisms and Therapeutic Potential
   5. Secondary Metabolites in Diabetes Management: Mechanisms of Action
   6. Anti-inflammatory and Antioxidant Properties of Secondary Metabolites in Metabolic Health
   7. Anti-Hyperlipidemic Effects of Plant-Derived Secondary Metabolites
   8. Metabolomics in Studying Cardiometabolic Effects of Secondary Metabolites
   9. Molecular Mechanisms of Secondary Metabolites in Metabolic Disorder Prevention and Treatment
   10. The Impact of Secondary Metabolites on Epigenetic Regulation and Gut Microbiota
   11. Advances in Formulation and Delivery Systems for Cardiometabolic Therapeutics
   12. Regulatory Hurdles in Secondary Metabolite-Based Drug Formulations