The book is a curated collection of groundbreaking papers entrenched in evidence-based medicine to provide trainees and practitioners in critical care medicine with a handy tool for reference. This compilation highlights pivotal research papers that have significantly influenced clinical practice. The studies in this book are carefully selected based on a rigorous methodology and cover a wide range of critical topics. The studies present robust findings and offer guidance on improving clinical outcomes.

Critical care medicine is a relatively new area of specialization and many contentious topics have been the focus of research over the years. In the contemporary era of evidence-based medicine, researchers continue to search for reliable evidence. Despite an abundance of research, few papers have truly shaped the landscape. The book presents an overview of critical care research that has significantly influenced the field and impacted clinical practice. These studies represent landmarks in the history of critical care medicine, spearheaded by leaders in their research.

The book is designed to appeal to both trainees and practitioners in the field of critical care medicine.

Provides evidence-based training and practice in the contemporary era Includes presentation of papers in the PICO format (population, intervention, comparison, outcomes) Covers readable summary of groundbreaking papers in critical care medicine with background and historical evidence

Autorentext

Dr. Jose Chacko, MD, DA, DNB, EDIC, MBA, graduated in medicine and completed post-graduation in anesthesia from Medical College, Trivandrum, India. He underwent advanced training in critical care medicine from leading hospitals in Australia and worked as a consultant in anesthesia and critical care with the National Health Services in the United Kingdom. He has completed the European Diploma in Intensive Care (EDIC) from the European Society of Intensive Care Medicine (ESICM) and currently works as a senior consultant in critical care medicine at Narayana Health, Bangalore, India. A renowned teacher and academician, he is a leading practitioner and teacher of critical care medicine in India. He has many publications in peer-reviewed journals and contributed to text books in critical care and emergency medicine. He contributes regularly to academic meetings in critical care medicine. Dr. Chacko runs a blog site (criticalcareblogspot.com) and creates podcasts (critcareedu.com.au) that address provocative topics in critical care medicine. Dr. Swapnil Pawar, MD, FCICM, EDIC, completed his post-graduation in anesthesia in 2010 from the Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. He is a fellow of the College of Intensive Care Medicine (FCICM), Australia and New Zealand and has also completed his European Diploma in Intensive Care (EDIC) with the European Society of Intensive Care Medicine (ESICM). He is currently working as a consultant intensivist at the St. George Hospital in Sydney and is the coordinator for Innovation in Intensive Care. He is the chair of the education committee of the Australia and New Zealand Intensive Care Society (ANZICS). He has a keen interest in simulation and medical education and is a certified simulation healthcare educator (CHSE) with the Society of Simulation in Healthcare (SSH). He is the host and producer of six educational podcast series andruns his educational website Critical Care Education (www.critcareedu.com.au). He is currently pursuing his Ph.D. in the field of cognitive load theory and has delivered numerous oral and posters presentations at international meetings. He is a trained mediator and enjoys grooming young talent as a captain of St George district cricket club metro team. Professor Ian Seppelt, FANZCA, FCICM, graduated in medicine from the University of Sydney, Australia. He is a senior specialist in intensive care medicine at Nepean Hospital, University of Sydney, professor of anesthesia at Macquarie University, and professorial fellow at The George Institute for Global Health, Sydney. He has more than 100 peer-reviewed international publications and has delivered numerous invited presentations at international meetings. He is a past executive member of the ANZICS Clinical Trials Group and lead investigator for SuDDICU (Australia) for which he received a National Health and Medical Research Council Research Excellence Award in 2015. He is on the management committees for several clinical trials including SuDDICU, SPICE-IV, and REMAP-CAP. He chairs the Nepean Blue Mountains Local Health District Human Research Ethics Committee (HREC) and is a member of various data safety monitoring boards. He is a medical advisor to Equestrian Australia and assistant groom and transport technician for his wife and children when they are competing. Dr. Gagan Brar, MD, DNB, EDIC, IDCCM, graduated in medicine and completed post-graduation in anesthesia from Kasturba Medical College, Manipal, India. She underwent training in critical care medicine at Manipal Hospital and Fortis Hospital, Bangalore, India. She is a fellow of the National Board of Examinations in critical care medicine and has completed the European diploma in intensive care (EDIC) with the European Society of Intensive Care Medicine (ESICM). She currently works as a consultant in critical care medicine, Aster RV Hospital,

Inhalt

Part I: Mechanical Ventilation and Respiratory Failure .- 1. Neuromuscular Blockers in Acute Respiratory Distress Syndrome: The ACURASYS Trial.-2. Ventilation with Low Tidal Volumes in Acute Respiratory Distress Syndrome: The ARDS-Net Trial.- 3. Prone Ventilation in Severe Acute Respiratory Distress Syndrome: The PROSEVA Trial.- 4. Timing of Tracheostomy: Early vs. Late Tracheostomy in Mechanically Ventilated Patients: The TRACMAN Trial.- 5. High-Frequency Oscillation in Acute Respiratory Distress Syndrome: The OSCILLATE Trial.- 6. High-Frequency Oscillation in Acute Respiratory Distress Syndrome: The OSCAR Trial.- 7. Positive End-Expiratory Pressure Setting in Acute Respiratory Distress Syndrome: The EXPRESS Trial.- 8. Comparison of Different Methods of Weaning from Mechanical Ventilation: Esteban et al.- 9. Noninvasive Ventilation for Chronic Obstructive Pulmonary Disease: Brochard et al.- Part II: Fluid Management .- 10. Albumin vs. Normal Saline for Resuscitation: The SAFE Trial.- 11. Albumin Replacement in Severe Sepsis and Septic Shock: The ALBIOS Trial.- 12. Hydroxyethyl Starch vs. Normal Saline for Fluid Resuscitation: The CHEST Trial.- 13. Balanced Crystalloid vs. Normal Saline for Resuscitation: The SMART Trial.- 14. Balanced Crystalloid vs. Normal Saline for Resuscitation: The BaSICS Trial.- 15. Balanced Multielectrolyte Solution vs. Normal Saline for Resuscitation: The PLUS Trial.- 16. Conservative vs. Liberal Fluid Management in ARDS: The FACTT Trial.- Part III: Cardiopulmonary Resuscitation .- 17. Compression-Only Cardiopulmonary Resuscitation in Out-of-Hospital Cardiac Arrest: The DART Trial.- Part IV: Neurosciences .- 18. Intracranial Pressure Monitoring and Outcomes in Traumatic Brain Injury: The BEST-TRIP Trial.- 19. Methylprednisolone in Severe Traumatic Brain Injury: The CRASH Trial.- 20. Thrombectomy at 6 to 24 Hours Following Stroke with Mismatch Between Deficit and Infarct Size: The DAWN Trial.- 21. Decompressive Craniectomy in Severe Diffuse Traumatic Brain Injury: The DECRA Trial.- 22. Decompressive Craniectomy for Intracranial Hypertension Following Traumatic Brain Injury: The RESCUEicp Trial.- 23. Decompressive Craniectomy in Older Patients with Extensive Middle-Cerebral-Artery Stroke: The DESTINY II Trial.- 24. Intravenous Thrombolysis Between 34.5 Hours After Stroke: The ECASS 3 Trial.- 25. A Comparison of Four Treatments for Generalized Convulsive Status Epilepticus: Treiman et al.- 26. Neurosurgical Clipping vs. Endovascular Coiling in Ruptured I…