The third edition of this book on name reactions contains major improvements over the previous edition. In addition to updated references, each reaction is now supplemented with two to three representative examples in synthesis to showcase its synthetic utility. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Furthemore, the subject index is significantly expanded.

This book differs from others on name reactions in organic chemistry by focusing on their mechanisms. It covers over 300 classical as well as contemporary name reactions. Each reaction is delineated by its detailed step-by-step, electron-pushing mechanism, supplemented with the original and the latest references, especially review articles. Thus, it is not only an indispensable resource for senior undergraduate and graduate students for learning and exams, but also a good reference book for all chemists interested in name reactions.

Many chemists collect named and unnamed reactions and their mechanisms Will make this time-consuming effort redundant Gives the earliest and latest references to these name reactions Gives representative examples in synthesis

Autorentext

Bevor er als Vice President of Discovery Chemistry zu ChemPartner kam, war Dr. Jie Jack Li über zwanzig Jahre lang in der medizinischen Chemie bei Pfizer, BMS bzw. Revolution Medicines tätig und lehrte vier Jahre lang als außerordentlicher Professor an der Universität von San Francisco medizinische und organische Chemie. Er hat dreißig Bücher über organische Chemie, medizinische Chemie und die Geschichte der Arzneimittelentdeckung veröffentlicht. Die wichtigsten davon sind Drug Discovery: Practices, Processes, and Perspectives und Name Reactions, jetzt in der sechsten Auflage.

Klappentext

The third edition contains major improvements over the previous edition. In addition to updated references, each reaction is now supplemented with two to three representative examples in synthesis to showcase its synthetic utility. Biographical sketches for the chemists who discovered or developed those name reactions have been included. Furthemore, the subject index is significantly expanded.

Different from other books on name reactions in organic chemistry, Name Reactions, A Collection of Detailed Reaction Mechanisms focuses on their mechanisms. It covers over 300 classical as well as contemporary name reactions. Each reaction is delineated by its detailed step-by-step, electron-pushing mechanism, supplemented with the original and the latest references, especially review articles. Thus, it is not only an indispensable resource for senior undergraduate and graduate students for learning and exams, but also a good reference book for all chemists interested in name reactions.

Some praise for the previous edition:

"This is an excellent book for arrow pushing and learning organic name reactions as encountered in graduate school . . . Li's book contains reactions of all mechanistic classes . . . The book is nicely balanced, containing modern-day reactions for assembly of stereocomplex molecules. Reactions such as the Corey-Bakshi-Shibata reduction are analyzed. This book is a good reference text that fills a void that has existed for some time. It is both an excellent tool for learning and a good reference source."

JOURNAL OF CHEMICAL EDUCATION

Inhalt
Alder ene reaction.- Aldol condensation.- Algar-Flynn-Oyamada Reaction.- Allan-Robinson reaction.- Appel reaction.- Arndt-Eistert homologation.- Baeyer-Villiger oxidation.- Baker-Venkataraman rearrangement.- Bamberger rearrangement.- Bamford-Stevens reaction.- Barbier coupling reaction.- Bargellini reaction.- Bartoli indole synthesis.- Barton radical decarboxylation.- Barton-McCombie deoxygenation.- Barton nitrite photolysis.- Barton-Zard reaction.- Batcho-Leimgruber indole synthesis.- Baylis-Hillman reaction.- Beckmann rearrangement.- Beirut reaction.- Benzilic acid rearrangement.- Benzoin condensation.- Bergman cyclization.- Biginelli pyrimidone synthesis.- Birch reduction.- Bischler-Möhlau indole synthesis.- Bischler-Napieralski reaction.- Blaise reaction.- Blanc chloromethylation.- Blum aziridine synthesis.- Boekelheide reaction.- Boger pyridine synthesis.- Borch reductive amination.- Borsche-Drechsel cyclization.- Boulton-Katritzky rearrangement.- Bouveault aldehyde synthesis.- Bouveault-Blanc reduction.- Boyland-Sims oxidation.- Bradsher reaction.- Brook rearrangement.- Brown hydroboration.- Bucherer carbazole synthesis.- Bucherer reaction.- Bucherer-Bergs reaction.- Büchner-Curtius-Schlotterbeck reaction.- Büchner method of ring expansion.- Buchwald-Hartwig C-N and C-O bond formation reactions.- Burgess dehydrating reagent.- Cadiot-Chodkiewicz coupling.- Camps quinolinol synthesis.- Cannizzaro disproportionation.- Carroll rearrangement.- Castro-Stephens coupling.- Chan alkyne reduction.- Chan-Lam coupling reaction.- Chapman rearrangement.- Chichibabin pyridine synthesis.- Chugaev elimination.- Ciamician-Dennsted rearrangement.- Claisen condensation.- Claisen isoxazole synthesis.- Claisen rearrangements.- Clemmensen reduction.- Combes quinoline synthesis.-Conrad-Limpach reaction.- Cope elimination reaction.- Cope rearrangement.- Corey-Bakshi-Shibata (CBS) reduction.- Corey-Chaykovsky reaction.- Corey-Fuchs reaction.- Corey-Kim oxidation.- Corey-Nicolaou macrolactonization.- Corey-Seebach reaction.- Corey-Winter olefin synthesis.- Criegee glycol cleavage.- Criegee mechanism of ozonolysis.- Curtius rearrangement.- Dakin oxidation.- Dakin-West reaction.- Danheiser annulation.- Darzens glycidic ester condensation.- Davis chiral oxaziridine reagents.- Delépine amine synthesis.- de Mayo reaction.- Demjanov rearrangement.- Dess-Martin periodinane oxidation.- Dieckmann condensation.- Diels-Alder reaction.- Dienone-phenol rearrangement.- Di-?-methane rearrangement.- Doebner quinoline synthesis.- Dötz reaction.- Dowd-Beckwith ring expansion.- Erlenmeyer-Plöchl azlactone synthesis.- Eschenmoser-Tanabe fragmentation.- Eschweiler-Clarke reductive alkylation of amines.- Evans aldol reaction.- Favorskii rearrangement and quasi-Favorskii rearrangement.- Feist-Bénary furan synthesis.- Ferrier carbocyclization.- Ferrier glycal allylic rearrangement.- Fiesselmann thiophene synthesis.- Fischer indole synthesis.- Fischer oxazole synthesis.- Fleming-Kumada oxidation.- Friedel-Crafts reaction.- Friedländer quinoline synthesis.- Fries rearrangement.- Fukuyama amine synthesis.- Fukuyama reduction.- Gabriel synthesis.- Gabriel-Colman rearrangement.- Gassman indole synthesis.- Gattermann-Koch reaction.- Gewald aminothiophene synthesis.- Glaser coupling.- Gomberg-Bachmann reaction.- Gould-Jacobs reaction.- Grignard reaction.- Grob fragmentation.- Guareschi-Thorpe condensation.- Hajos-Wiechert reaction.- Haller-Bauer reaction.- Hantzsch dihydropyridine synthesis.- Hantzsch pyrrole synthesis.- Heck reaction.- Hegedus indole synthesis.-Hell-Volhard-Zelinsky reaction.- Henry nitroaldol reaction.- Hinsberg synthesis of thiophene derivatives.- Hiyama cross-coupling reaction.- Hofmann rearrangement.- Hofmann-Löffler-Freytag reaction.- Horner-Wadsworth-Emmons reaction.- Houben-Hoesch reaction.- Hunsdiecker-Borodin reaction.- Hurd-Mori 1,2,3-thiadiazole synthesis.- Jacobsen-Katsuki epoxidation.- Japp-Klingemann hydrazone synthesis.- Jones oxidation.- Julia-Kocienski olefination.- Julia-Lythgoe olefination.- Kahne-Crich glycosidation.- Keck macrolactonization.- Knoevenagel condensation.- Knorr pyrazole synthesis.- Koch-Haaf carbonylation.- Koenig-Knorr glycosidation.- Kolbe-Schmitt reaction.- Kostanecki reaction.- Kröhnke pyridine synthesis.- Kumada cross-coupling reaction.- Lawesson's reagent.- Leuckart-Wallach reaction.- Lossen rearrangement.- McFadyen-Stevens reduction.- McMurry coupling.- MacMillan catalyst.- Mannich reaction.- Marshall boronate fragmentation.- Martin's sulfurane dehydrating reagent.- Masam…