When Critical Issues in Psychiatry was conceived, there were several sub jects I considered to be of crucial importance in a series devoted to residents and clinicians in psychiatry, as well as to other mental health professionals. Of prominence was the pressing need for an in-depth and scholarly exam ination of the interface between medicine and psychiatry. I had been amazed to find that not a single book, to my mind, adequately addressed the psy chological symptoms and manifestations of both common and rare medical illness. It seemed to me that there was a need for a work which would achieve the following goals: First, it would assist in the differential diagnosis of functional psychiatric symptoms versus symptoms secondary to recog nized or unrecognized medical illness; second, it would elucidate the psy chological symptoms resulting from pharmacologic and other therapeutic interventions in medical illness; and third, it would examine the use of psychopharmacological agents in the presence of medical illness and the drugs used to treat that illness. Dr. Jefferson is Board Certified in both internal medicine and psychiatry, and both Drs. Jefferson and Marshall have extensive clinical experience from their many years of consultation/liaison work in psychiatry. Their experience and expertise have resulted in what I believe to be a monumental contri bution to the literature.

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When Critical Issues in Psychiatry was conceived, there were several sub­ jects I considered to be of crucial importance in a series devoted to residents and clinicians in psychiatry, as well as to other mental health professionals. Of prominence was the pressing need for an in-depth and scholarly exam­ ination of the interface between medicine and psychiatry. I had been amazed to find that not a single book, to my mind, adequately addressed the psy­ chological symptoms and manifestations of both common and rare medical illness. It seemed to me that there was a need for a work which would achieve the following goals: First, it would assist in the differential diagnosis of functional psychiatric symptoms versus symptoms secondary to recog­ nized or unrecognized medical illness; second, it would elucidate the psy­ chological symptoms resulting from pharmacologic and other therapeutic interventions in medical illness; and third, it would examine the use of psychopharmacological agents in the presence of medical illness and the drugs used to treat that illness. Dr. Jefferson is Board Certified in both internal medicine and psychiatry, and both Drs. Jefferson and Marshall have extensive clinical experience from their many years of consultation/liaison work in psychiatry. Their experience and expertise have resulted in what I believe to be a monumental contri­ bution to the literature.

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1 Physical Illness and Psychiatric Symptoms.- Overview.- Representative Psychiatric Symptoms.- References.- 2 Cardiovascular Disorders.- Heart Failure.- Arrhythmias.- Blood Pressure.- Atherosclerotic Heart Disease.- Syncope.- Cardiac Tumors.- Infective (Bacterial) Endocarditis.- Functional Cardiac Disorders.- Mitral Valve Prolapse Syndrome (MVPS).- Impotence.- Thoracic Outlet Syndrome.- Carotidynia.- Giant Cell Arteritis, Temporal Arteritis, Polymyalgia Rheumatica.- Neuropsychiatric Effects of Cardiovascular Drugs.- Cardiovascular Drug-Induced Sexual Dysfunction.- Psychotropic Drugs and Cardiovascular Disorders.- References.- 3 Respiratory Disorders.- Respiratory Failure.- Hyperventilation (Respiratory Alkalosis).- Dyspnea.- Asthma.- Pulmonary Embolism.- Hiccup.- Diaphragmatic Flutter (Respiratory Myoclonus, Leeuwenhoek Disease).- Psychotropic Drugs and Respiratory Disorders.- Neuropsychiatric Effects of Respiratory Drugs.- References.- 4 Renal Disorders.- Renal Failure.- Psychotropic Drugs and Renal Disorders.- References.- 5 Gastrointestinal Disorders.- Alimentary Tract Disorders.- Pancreatic Disorders.- Hepatic Disorders.- References.- 6 Endocrine Disorders.- Adrenal Disorders.- Thyroid Disorders.- Parathyroid Disorders.- Hypoglycemic Disorders.- References.- 7 Fluid-Electrolyte,AcidBase Disorders.- AcidBase Disorders.- Sodium.- Potassium.- Magnesium.- Calcium.- Phosphorus.- Psychiatric-Drug-Induced FluidElectrolyte Disorders.- References.- 8 Metabolic Disorders.- Porphyria.- Wilson Disease (Hepatoenticular Degeneration).- References.- 9 Connective Tissue Disorder (Systemic Lupus Erythematosus).- Clinical Features.- Laboratory Findings.- Neuropsychiatric Features.- Treatment.- References.- 10 Striated Muscle Disorder (Myasthenia Gravis).- Definition.-Clinical Features.- Clinical Classification.- Neuropsychiatric Features.- Pathogenesis.- Diagnosis.- Treatment.- Neuropsychiatric Effects of Antimyasthenic Drugs.- The Use of Psychotropic Drugs in Patients with Myasthenia Gravis.- References.- 11 Vitamin Disorders.- Hypervitaminosis A.- Thiamine (Vitamin B1) Deficiency.- Niacin (Nicotinic Acid) Deficiency.- Vitamin B6 Deficiency.- Vitamin B12 and Folic Acid Deficiencies.- Ascorbic Acid (Vitamin C) Deficiency.- References.- 12 Infectious Disorders.- Viral Encephalitis.- Infectious Mononucleosis.- Neuropsychiatric Effects of Infectious Disease Drugs.- References.- 13 Toxin Disorders.- Mercury.- Lead.- Bismuth.- Arsenic.- Bromides.- Organophosphate.- References.- 14 Skin Disorders.- Burn Delirium.- Psychotropic Drug-Induced Dermatologic Disorders.- References.- 15 Reproductive and Sexual Function Disorders.- Premenstrual Syndrome.- Oral Contraceptives.- Sexual Dysfunction (Impotence).- References.- 16 Sleep and Arousal Disorders.- Diagnostic Classification.- Specific Disorders.- Miscellaneous Conditions.- Conclusion.- References.- 17 Substance Abuse Disorders.- Caffeine.- Alcohol.- Amphetamines and Amphetamine-like Drugs.- Cannabis (Marijuana).- Opiates and Synthetic Analgesics (Opioids).- Hallucinogens and Phencyclidine.- References.