Autorentext
Dr. Elaine Jaffe is regarded by her peers as one of the most pre-eminent hematopathologists of her generation. She is most widely known for her work regarding the pathophysiology and prognosis of malignant lymphomas, as well as her unparalleled work to understand how they respond to treatment. Dr. Jaffe led the effort to develop the World Health Organization classification of tumors of the hematopoietic and lymphoid tissues published in 2001, a classification that rapidly became the international standard. Dr. Daniel Arber is an internationally recognized expert in the diagnosis and classification of hematopoietic tumors, including malignant lymphoma, acute and chronic leukemia, myeloproliferative disorders, myelodysplastic syndrome and tumors of the spleen.the clinical director of the Biomedical Diagnostic Centre of Hospital Clinic and a full Professor of Anatomical Pathology at the University of Barcelona, where he also teaches in the Department of Anatomical Pathology, Pharmacy and Microbiology. He is the Spanish coordinator of the International Cancer Genome Consortium.Professor Dr. Leticia Quintanilla de Fend, head of the Core Facility and Senior Physician at the Institute of Pathology has extensive experience in the interpretation of mouse models. From 2000 until 2008 she was a director of the mouse pathology at the Institute of Pathology of the Helmholtz Center Munich and the Pathology Screen of the German Mouse Clinic (GMC) and established various special procedures for the analysis of mouse models. Professor Quintanilla de Fend is involved in the establishment of standards in the pathology of mouse models within EU networks.Dr. Attilio Orazi is an internationally renowned academic hematopathologist whose diagnostic expertise spans all areas of hematopathology. However, he is best known for his expertise and scholarly accomplishments as a bone marrow pathologist. He is a member of the Scientific Committee of the European Bone Marrow Working Group, has directed courses concerning the assessment of bone marrow disorders and splenic pathology at the United States and Canadian Academy of Pathology and was the co-organizer of the 2007 Workshop of the Society of Hematopathology.

Klappentext
Selected for 2025 Doody’s Core Titles® with "Essential Purchase" designation in Surgical Pathology

Covering the broad range of benign and malignant disorders that affect the hematopoietic system, Hematopathology, 3rd Edition, remains your #1 source of authoritative information in this fast-changing field. Edited by Dr. Elaine Jaffe and a team of globally renowned, expert co-editors, it offers a wealth of up-to-date information in an easily accessible format, equipping you to deliver more accurate and actionable pathology reports. Comprehensive in scope, this highly illustrated, practical text is a must-have resource for residents and practicing pathologists alike.

• Helps you navigate the latest changes in the classification of hematolymphoid neoplasms, providing guidance for use of both the International Consensus Classification (ICC) and 5th edition of the WHO classification
• Incorporates the latest molecular/cytogenetic information, regarding newly recognized entities and the latest diagnostic criteria
• Provides you with today's most effective guidance in evaluating specimens from the lymph nodes, bone marrow, peripheral blood, and more, with authoritative information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each
• Details the latest insights on the molecular biology of benign and malignant hematologic disorders
• Features more than 1,100 high-quality color images that mirror the findings you encounter in practice
• Uses an easy-to-navigate, templated format with standard headings in each chapter.
• Includes information on disease progression and prognosis, helping you better understand the clinical implications of diagnosis
• Shares the knowledge and expertise of new editors, Drs. Lisa Rimsza, Attilio Orazi, and Steven Swerdlow, providing expertise in molecular diagnostics, bone marrow and lymph node biopsies

• An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

  Inhalt

  PART I Technical Aspects

  1. Processing of the Lymph Node Biopsy Specimen
  2. Fine-Needle Aspiration of Lymph Nodes
  3. Immunohistochemistry for the Hematopathology Laboratory
  4. Flow Cytometry
  5. Molecular Pathology of Hematologic Neoplasms
  6. Important Chromosomal Aberrations in Hematologic Neoplasms and Key Techniques to Diagnose Them

  PART II Normal and Reactive Conditions of Hematopoietic Tissues

  7. Normal Lymphoid Organs and Tissues
  8. Reactive Lymphadenopathies
  9. The Normal Bone Marrow
  10. Evaluation of Anemia, Leukopenia, and Thrombocytopenia
  11. Bone Marrow Findings in Inflammatory, Infectious, and Metabolic Disorders

  PART III Lymphoid Neoplasms

  12. Principles of Classification of Lymphoid Neoplasms

  SECTION 1 MATURE B-CELL NEOPLASMS

  13. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Monoclonal B-Cell Lymphocytosis, and B-Cell Prolymphocytic Leukemia
  14. Lymphoplasmacytic Lymphoma and Waldenström Macroglobulinemia
  15. Hairy Cell Leukemia
  16. Splenic Marginal Zone Lymphoma and Other Small B-Cell Neoplasms in the Spleen
  17. Follicular Lymphoma
  18. Extranodal Marginal Zone Lymphoma: MALT Lymphoma
  19. Primary Cutaneous B-Cell Lymphomas
  20. Nodal Marginal Zone Lymphoma
  21. Mantle Cell Lymphoma
  22. Aggressive B-Cell Lymphomas Including Diffuse Large B-Cell Lymphoma, Not Otherwise Specified and Other Nodal and Extranodal Large B-Cell Lymphomas
  23. Burkitt Lymphoma, High-Grade B-Cell Lymphoma Not Otherwise Specified, High-Grade B-Cell Lymphoma With MYC and BCL2/BCL6 Rearrangements, Large B-Cell Lymphoma With 11q Aberration, and Provisional Entity High-Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements
  24. Plasmablastic Neoplasms Other Than Plasma Cell Myeloma
  25. Plasma Cell Neoplasms
  26. Nodular Lymphocyte-Predominant B-Cell Lymphoma
  27. Classic Hodgkin Lymphoma
  28. Virally Associated B-Cell Lymphoproliferative Disease

  SECTION 2 MATURE T-CELL AND NK-CELL NEOPLASMS

  29. Epstein-Barr Virus-Associated T-Cell and Natural Killer-Cell Lymphoproliferative Disorders
  30. T-Cell and NK-Cell Large Granular Lymphocyte Proliferations
  31. T-Cell Prolymphocytic Leukemia
  32. Adult T-Cell Leukemia/Lymphoma
  33. Hepatosplenic T-Cell Lymphoma
  34. Peripheral T-Cell Lymphoma, Not Otherwise Specified
  35. Follicular Helper T-Cell Lymphoma
  36. Anaplastic Large Cell Lymphoma, ALK Positive and ALK Negative
  37. Enteropathy-Associated T-Cell Lymphoma and Other Primary Intestinal T-Cell Lymphomas
  38. Mycosis Fungoides and Sézary Syndrome
  39. Primary Cutaneous CD30-Positive T-Cell Lymphoproliferative Disorders
  40. Primary Cutaneous T-Cell Lymphomas: Rare Subtypes

  SECTION 3 PRECURSOR B- AND T-CELL NEOPLASMS

  41. Precursor B-Cell and T-Cell Neoplasms
  42. Acute Leukemias of Ambiguous Lineage

  PART IV Myeloid, Histiocytic, and Related Proliferations

  43. Principles of Classification of Myeloid Neoplasms
  44. The Myelodysplastic Syndromes
  45. Myeloid and Hematologic Neoplasms With Germline Predisposition
  46. Acute Myeloid Leukemia
  47. Myeloproliferative Neoplasms
  48. Myelodysplastic/Myeloproliferative Neoplasms and Premalignant Conditions
  49. Mastocytosis
  50. Eosinophilia, Chronic Eosinophilic Leukemia, Not Otherwise Specified, and Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions
  51. Blastic Plasma…