Innovative Surface Modifications in Biomaterials

Autorentext

Navdeep Singh Grewal recently concluded his postdoctoral research at the University of South Bohemia, Czech Republic, where his work focused on advanced biomaterials and surface engineering, currently serving as Assistant Professor in the Department of Mechanical Engineering, Guru Kashi University, Talwandi Sabo, India. He is a highly accomplished researcher in biomaterials science and engineering. He has expertise spanning interdisciplinary studies in metallurgical materials, mechanical, and biomedical engineering. His research focuses on the development and characterization of biodegradable biomaterials functionalized with composite and hybrid coatings, for orthopedic applications. His research has led to numerous high-impact publications and collaborations, establishing him as a leading expert in the field.

Gurpreet Singh Saini is an Assistant Professor-III in the Department of Automobile and Aeronautical Engineering, Amity Institute of Technology, Amity University Uttar Pradesh (AUUP), Noida, India. He received his Ph.D. degree in Mechanical Engineering (Composite Materials) from J. C. Bose University of Science and Technology, YMCA in 2017. He has more than 10 years of teaching and research experience with core areas of research in Composite Materials, Material characterization, process optimization, wear and Tribology. He is an active Life Member of Science and Engineering Institute (SCIEI). He has also contributed to more than 25 research papers in various international journals of repute.

Neeraj Sharma is an Associate Professor at Production Engineering Department of National Institute of Technology Agartala. He has published more than 100 research articles in various conferences and journals of repute. His main area of research interests are biomaterials, composites, bio-composites, additive manufacturing and optimizations using statistical/AI techniques.

Yogesh Kumar Singla is an Assistant Professor of Mechanical Engineering at Navajo Technical University and an Adjunct Research Associate at Harvard University. His interdisciplinary research integrates sustainable materials, additive manufacturing, and surface engineering to develop durable, resource-efficient systems that advance the circular economy and energy-efficient manufacturing.

Anil Mahapatro is Associate Dean and Professor of Biomedical Engineering at Wichita State University, Kansas. His research focuses on surface modification of biomaterials, biodegradable implants, and nanostructured coatings for clinical translation. With over 60 publications, multiple innovation and excellence awards, and recognition as a Fellow of the Institution of Engineering and Technology (FIET, U.K.), he has made significant contributions to advancing biofunctional surfaces and sustainable healthcare technologies.

Klappentext

This book provides a comprehensive exploration of the wide spectrum of surface modifications employed in biomaterials to meet various clinical needs. It addresses mechanical, thermal, and chemical modifications, detailing the challenges, advantages, and target applications associated with each technique. Innovative coating architectures can be designed to offer different bio-functionalities including targeted drug delivery (e.g., site-specific adhesion) or biomimetic tissue regeneration; anti-bacterial response (i.e., targeted bacterial adhesion); and stimulation of angiogenesis.

Though discussing both conventional and recent strategies for surface modifications, considerable priority is placed on hybrid/composite strategies, specifically the integration of two or more coating technologies to promote synergistic effects and improve clinical outcomes. Through thorough analysis and case examples, this book will demonstrate the incorporation of next generation coating technologies into clinical practice to provide new insights on next generation biomaterials for advanced patient care.

Underscoring the pivotal role of surface modification in advancing the safety, functionality, and longevity of biomedical implants, this book will be a valuable and definitive title for industry professionals, clinicians and researchers.

Inhalt

1. Introduction to Surface Modifications in Biomaterials. 2. Mechanical Behaviour of Bio-Materials: Fundamentals, Structure-Property Relationships, and Advanced Characterization Techniques. 3. Surface-Substrate Interactions Under Mechanical Loading. 4. Characterization Techniques: Nanoindentation, Tribometry, and Mechanical Testing on Biomaterials. 5. Tribological Aspects and Surface Integrity of Advanced Surface-Modified Biomaterials. 6. Mechanical Degradation Mechanisms. 7. Mechanical Design of Surface-Modified Biomaterials. 8. Surface Chemistry and Materials Science of Biomaterial Interfaces. 9. Multifunctional Coatings for Enhanced Clinical Performance. 10. Design Principles for Surface Architecture and Coating Stability. 11. Advanced Surface Modification Techniques for Biomaterials: From Plasma Engineering to Smart and Bioinspired Interfaces. 12. Hybrid and Composite Surface Engineering Approaches. 13. Self-Cleaning and Self-Healing Surface Coatings. 14. Surface Modification Strategies for Targeted Drug Delivery and Tissue Regeneration. 15. Digital Twins and Computational Modelling of Surface Modifications. 16. Future Directions and Roadmap for Next-Generation Biomaterials.