Hormone Use and Abuse by Athletes

Physical activity exerts an important influence on the endocrine system, modulating synthesis and secretion of several hormones. Almost every organ and system in the body is affected by physical activity and exercise, mainly through the endocrine and neuroendocrine system. Mode, intensity, and duration of the exercise bout, age, gender and fitness level of the individual as well as environmental and psychological factors may affect the endocrine response to physical activity.

On the other hand, several hormones are able to influence physical performance and body composition. Thus, a bi-univocal interrelationship between exercise and hormones exists.

In this book new developments on metabolic and endocrine response to exercise are revised and introduce the "hot topic" of hormonal doping in sports. In the past decades, hormone abuse has become a widespread habit among professional and most of all and more frequently recreational athletes. A substantial part of this volume is devoted to the effects of exogenous hormones on performance. Anabolic steroids, growth hormone and erythropoietin properties, use and misuse in sports are widely described. Specific methods to detect hormone abuse are presented and discussed.

The contributors to this volume are well-known experts and dedicated researchers in the fields of sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection.

The purpose of this volume is to provide all professionals involved in sports medicine and endocrinology a state-of-the-art overview of the complex interactions between physical activity and the endocrine system and to focus on hormone abuse in sports at competitive and recreational level highlighting its negative consequences for long-term health.

Current scientific and clinical data will be provided on hormone use by athletes - vital for clinicians caring for patients in both the professional and non-professional athletic arenas. International authors renowned with a compact and comprehensive volume. Includes supplementary material: sn.pub/extras

Klappentext
Several hormones are able to influence physical performance and body composition. Thus, a bi-univocal interrelationship between exercise and hormones exists. In Hormone Use and Abuse by Athletes, new developments on metabolic and endocrine responses to exercise are revised and the topic of hormonal doping in sports is introduced. In the past decades, hormone abuse has become a widespread habit in professional andmost of all and more frequentlyrecreational performance. Anabolic steroids, growth hormones and erythropoietin properties use and misuse in sports are widely described. Specific methods to detect hormone abuse are presented and discussed. The contributors to this volume are well-known experts and dedicated researchers in the fields of sports medicine and endocrinology, endocrine physiology, pharmacology, and doping detection. The purpose of this volume is to provide all professionals involved in sports medicine and endocrinology a state-of-the-art overview of the complex interactions between physical activity and the endocrine system and to focus on hormone abuse in sports at competitive and recreational levels, highlighting its negative consequences for long-term health. In this very topical volume, the editors have assembled an expert panel of authors addressing one of the most significant challenges in sports medicine todaythe use and abuse of hormones in competitive sports. The chapters provide up-to-date, clearly written information ranging from physiology of the pituitary axes in exercise and sports, impact of reproductive function illicit hormonal abuse, and assay methods and compelling pitfalls for rigorous detection of sports doping. This volume will be of great utility to sports physicians, exercise physiologists and endocrinologists, as well as to scientific and sports regulatory agencies and ethicists grappling with responding to this societal challenge. - Shlomo Melmed, M.D. Series Editor

Inhalt
GH/IGF-I Axis In Exercise.- Exercise, Training and the Hypothalamo-Pituitary-Adrenal Axis.- Thyroid Axis, Prolactin and Exercise.- Exercise, Training and the Hypothalmic-Pituitary-Gonadal Axis in Men.- Exercise and the Reproductive System in Women.- Physical Exercise, Sports and Diabetes.- Motor Performance and Muscle Mass as Function of the Hormonal Responses to Exercise.- Sports, Hormones and Doping in Children and Adolescents.- Androgen Abuse.- Growth Hormone.- Erythropoietin.- Amino Acids and Non-Hormonal Compounds for Doping in Athletes.- The Assay of Endogenous and Exogenous Anabolic Androgenic Steroids.- Problems With Growth Hormone Doping In Sports: Isoform Methods.- Detection of Growth Hormone Doping In Sport Using Growth Hormone-Responsive Markers.- Distinction Between Endogenous and Exogenous Erythropoietin: Marker Methods.- Direct Methods For Distinction Between Endogenous and Exogenous Erythropoietin