This book focuses on both high-density lipoproteins (HDL) metabolism and related diseases from the perspectives of the world-class experts in HDL. Several chapters in this book provide the overall information about HDL metabolism via detailed discussion of HDL structures as well as several key molecules involved in its functions, such as SR-B1 and Cholesteryl Ester Transfer Protein Inhibitors and so on. The rest of this book illustrates the connection between HDL and several diseases that are the major concerns of people's health in many countries, and devotes to exploring the therapies of HDL related diseases. With a better understanding of the HDL metabolism and diseases, this book will benefit the audiences with interest in HDL from biomedicine to clinical practice.

Introduces the latest advances in HDLs from the world-class HDL experts' perspectives Helps understanding the relationships among HDL structure and function, as well as related diseases Sheds light on the invention of diagnoses and therapies of HDL-related diseases

Autorentext

Dr. Zheng, Lemin is a professor and Vice Chair of Institute of Cardiovascular Sciences, Health Science Center, Peking University, Beijing, China. He received his Ph.D. from Cleveland Clinic and Cleveland State University, USA. He has published more than 109 peer-reviewed articles, with over 3664 SCI citations and one US Patent. He serves as an editorial board member of magazines such as Biology, Cardiovascular Drugs and Therapy, Cardiovascular & Hematological Disorders - Drug Targets, Lipid & Cardiovascular Research, Chinese Journal of Cardiovascular Research, Chinese Journal of Arteriosclerosis; a reviewer for magazines such as Circulation, Nature Communication, Diabetologia, ACS Applied Materials & Interfaces, FASEB Journal, British Journal of Pharmacology, Free Radical Biology and Medicine, Cardiovascular Diabetology.

Inhalt
Chapter 1: HDL Structure.- Chapter 2: HDL and Cholesterol ester transfer protein (CETP).- Chapter 3: HDL and Endothelial Function.- Chapter 4: HDL and lipid metabolism.- Chapter 5: HDL and oxidation.- Chapter 6: Scavenger Receptor Class B Type I and HDL.- Chapter 7: ABCA1, ABCG1 and cholesterol homeostasis.- Chapter 8: HDL and ASCVD.- Chapter 9: HDL and Diabetes.- Chapter 10: HDL and sepsis.- Chapter 11: HDL mimetic peptides.- Chapter 12: HDL and microRNAs.- Chapter 13: HDL-kidney diseases.- Chapter 14: HDL and therapy.- Chapter 15: High-density lipoprotein and Surgery.