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Good Research Practice in Non-Clinical Pharmacology and Biomedicine

  • Fester Einband
  • 436 Seiten
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This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology... Weiterlesen
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Beschreibung

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Inhalt

1. Quality in Non-GxP Research Environment.- 2. Guidelines & Initiatives for Good Research Practice.- 3. Learning from principles of evidence-based medicine to optimize nonclinical research practices.- 4. General Principles of Preclinical Study Design.- 5. Resolving the tension between exploration and confirmation in preclinical biomedical research.- 6. Blinding and Randomization.- 7. Out of control? Managing baseline variability in experimental studies with control groups.- 8. Quality of Research Tools.- 9. Genetic background and sex: impact on generalizability of research findings in pharmacology studies.- 10. Building robustness intro translational research.- 11. Minimum information and quality standards for conducting, reporting, and organizing in vitro research.- 12. Minimum Information in In Vivo Research.- 13. A reckless guide to P-values: Local evidence, global errors.- 14. Electronic Lab Notebooks and Experimental Design Assistants.- 15. Data storage.- 16. Design of meta-analysis studies.- 17. Publishers' responsibilities in promoting data quality and reproducibility.- 18. Quality governance in biomedical research.- 19. Good Research Practice - Lessons from Animal Care & Use.- 20. Research collaborations and quality in research: foes or friends?.- 21. Costs of implementing quality in research practice.

Produktinformationen

Titel: Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Editor:
EAN: 9783030336554
ISBN: 3030336557
Format: Fester Einband
Herausgeber: Springer International Publishing
Genre: Medizin
Anzahl Seiten: 436
Gewicht: 816g
Größe: H241mm x B160mm x T29mm
Jahr: 2020
Auflage: 1st ed. 2020

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