This comprehensive volume is a contribution to a new se ries initiated by the NATO Panel on "Gell to Gell Signals in Plants and Animals". The book reflects the outcome of an NATO work shop and bri ngs to mi nd two im portant questions: consideri ng the mass of relevant I iteratu reavai- able, is there any necessity for a new series of books - and considering the flood of compa rable meetings - is there any point in workshops of this nature and their publication? In order to deal with such questions adequately, much more space would be needed than is available in a foreword. Thus, the answers must remain rather superficial and, of course, rather subjective. To simplify the issue, the question of publication can be narrowed down to two fac tors - the financial risk, undertaken by the publisher, and the scientific risk, borne by the editor. If the book is good (with respect to lay-out and content) it will be a success - nothing will be lost the people involved will enhance their reputation! We are left with the question of the usefulness of workshops. Without doubt, it is indeed a useful procedure for experts to come together, in an atmosphere of harmony, and freedom from external pressures and time limitations, to discuss a well-defined theme. Wether in agreement or disagreement, a fair and open forum can be expectet for a variety of contributions.

Klappentext

Proceedings of the NATO Advanced Workshop on Glial-Neuronal Communication in Development and Regeneration held at Castle Ringberg, Bavaria, FRG, June 9-15, 1985

Inhalt
Glial Cell Lineages.- From Neuroepithelium to Mature Astrocytes.- Experimental Models for Astrocyte Activation and Fibrous Gliosis.- Microglia in Culture.- Molecular Properties of Peripheral Glia.- Receptors and Antigens Expressed by Glial/Neuronal Cells During Ontogenesis.- Adrenergic- and Histamine-Receptors on Cultured Astrocytes: Electrophysiological and Autoradiographic Binding Studies.- Desipramine Treated C6 Glioma Cells Express Opiate Receptors; Unmasking or Induction?.- Expression of Recognition Molecules in the Cerebellum of Young and Adult Rats.- Myelin-Associated Glycoprotein (MAG) in Chicken Neuronal Crest Derivatives, Including Neurons.- Neurone-Glia Relationship in the Retina: Localization OF GABA Uptake and Endogenous GFAP and GABA Immunoreactivities.- Developmentally Regulated Glial and Neuronal Antigens Detected by Monoclonal Antibodies.- Expression of Recognition and Adhesion Molecules at the Glial-Neuronal Cell Surface.- Biosynthesis of the Neural Cell Adhesion Molecule (N-CAM): Glial, Muscle and Neuronal Forms of N-CAM Studied in Primary Rat Cell Cultures.- Neurite Outgrowth Induced by Adhesive Proteins.- Neuronal Adhesion to Components of the Extracellular Matrix and Control of Nerve Fiber Growth.- Glial-Neuronal Interactions.- Modulation by Neuronal Signals of Energy Substrate in the Glial Cells of Leech Segmental Ganglia.- Regulation of Astrocytic High Affinity Uptake of Transmitter Amino Acids by Neuronal Signaling.- Characterization of Glial Proteins Transferred into the Squid Giant Axon.- Do Glial Cells Compete with Afferent Fibers for Apposition to the Neuronal Surface in Development and Aging of the Nervous System? A Study in the Avian Ciliary Ganglion with References to Other Neurons.- Influence on Glial/Neuronal Cells by Hormones and Gangliosides- Trophic Factors and Informational Substances.- Factors Affecting the Survival and Maturation of Nerve Cells in Culture.- Glycoconjugate Metabolism, Accretion and Release During Neurite Outgrowth in Normal and Transformed Cells of Neuronal Origin.- In Vitro Analysis of Glial-Neuronal Communication During Cerebellum Ontogenesis.- Effect of Nerve Growth Factor and cAMP Analogues on Neuronal Differentiation in PC12Cells: Studies with an Inhibitor of cAMP-Dependent Protein Kinases.- Are Phosphotyrosine-Containing Proteins Induced by Nerve Growth Factor Stimulation of PC12 Cells?.- Chromaffin Cells: Modified Neurons that are Both Targets and Storage Sites of Neuronotrophic and Neurite Promoting Factors.- Neurotrophic and Neurite Promoting Activities in Astroglial Conditioned Medium.- Neurite-Promoting Factors for Spinal Neurons.- Putative Autoregulative Growth Factor in Conditioned Medium OF Serum-Free Grown Astrocytes.- Differentiation of Astrocyte Precursors From Mouse Cerebellum.- Isolation of Two Astroglial Growth Factors from Bovine Brain; Comparison with Other Growth Factors; Cellular Localization.- Glial Cell Development and Reactivity in Reaggregating Brain Cell Culture.- Trophic and Metabolic Couplings Between Astroglia and Neurons.- Repair Mechanisms During Neuronal Regeneration.- Neural Tissue Transplants Modify Response of the Immature Spinal Cord to Damage.- Conditions for Neuronal Survival and Growth as Assessed by the Intracerebral Transplantation Technique in Lesion Models of the Adult CNS.- Hippocampal Transplants: Synaptic Organization, their Use in Repair of Neuronal Circuits and Mouse to Rat Xenografting.- A Model of Neuronal Sprouting for Examining the Role of Glia in Axonal Growth.- Comparative Studies of the Astrocytic Membrane in Regenerativeand Non-Regenerative Central Nervous Systems.- Neural Tissue Transplants: Studies Using Tissue Culture Manipulations, Cell Marking Techniques and A Plasma Clot Method to Follow Development of Grafted Neurons and Glia.- Pharmacologic and Immunologic Approaches to the Problems of Posttraumatic Glial Proliferation Following CNS Damage.- Molecular Approach to the Role of Macrophages and Astrocytes in Nerve Growth and Regeneration.- Culturing of Neurons and Oligodendrocytes Bulk Isolated from the Same Brain of Young Adult Rats.- Myelination Remyelination.- Role of Galactocerebroside in the Formation of Peripheral Myelin.- Further Characterization of the Neuronal Cell Surface Protein Mitogenic for Schwann Cells.- Galactocerebroside Expression by Non-Myelin Forming Schwann Cells.- Molecular Organization of the Cell Membrane in Normal and Pathological Axons: Relation to Glial Contact.- Oligodendrocyte Differentiation: Quantitative Studies in Primary Cultures of Dissociated Fetal Rat Brain.- Myelin Palingenesis: the Reformation of Myelin by Mature Oligodendrocytes in the Absence of Neurons.- Oligodendrocytes Ensheath Carbon Fibres and Produce Myelin in Vitro.- Oligodendrocyte Proliferation: Its Relationship to Central Nervous System Remyelination.- Myelination in the Mouse by Transplanted Oligodendrocytes.