This textbook explores the fundamental qualitative and quantitative aspects of human physiology. It approaches biological and physiological processes and phenomena from a quantitative perspective, revealing how physiological problems can be mathematically formulated starting from simple laws of physics. The book addresses a broad range of topics, including: the statics and dynamics of circulation; muscle and sarcomere force-length and force-velocity relations, together with their mechanisms and functional consequences; subdivisions and meaning of the heat produced by muscle; locomotion, statics and dynamics of respiration; diffusion of gases and acid base equilibrium; phonation; general functions of the kidney and of the different sections of the nephron; changes in clearance with a substance's plasmatic concentration; pH regulation and the kidney; Donnan's equilibrium and its consequences; and the Nernst equation.

The book offers the ideal learning resource for students ofhuman physiology courses in medicine and biomedicine, as well as biomedical engineering and biophysics graduate students. An elementary grasp of mathematics and physics is sufficient to understand the content.

Highlights the marvelous strategies that Nature uses to solve difficult problems, such as isolated kidney auto-control, respiration-phonation meeting, and acid-base regulation, helping readers understand and appreciate them Links between sequentially taught topics and outside world experience are frequently made to associate knowledge as a single unit, which can be easily applied to different external conditions The simple experimental procedures and mathematical methods used help readers understand complex mechanisms such as blood circulation and respiration, osmotic work in the kidney, and oxygen diffusion to hemoglobin

Autorentext

Giovanni A. Cavagna is Emeritus Professor of Human Physiology at State University of Milan, Italy. His research has mainly focused on biomechanics and biophysics.

Inhalt
Circulation of blood.- Muscle, locomotion and heart.- Respiration.- Kidney.