This book provides thorough coverage of high-throughput OMICs technologies for the monitoring of stem cells and regenerative medicine. Specific topics covered include the genomics, proteomics, and metabolomics aspects of regenerative medicine, metabolic profiling of mesenchymal stem cells, genome profiling of mesenchymal stem cells, OMICs monitoring of stem cell-derived exosomes, stem cell proteomics, lipidomics, OMICs profiling of cancer (stem) cells, and finally ethical considerations of OMICs-based investigations. Chapters are authored by world-renowned scientists who have valuable expertise in the field of OMICs and regenerative medicine.

Genomics, Proteomics, and Metabolomics: Stem Cells Monitoring in Regenerative Medicine, part of Springer's Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers, clinicians, biologists, biochemists, and pharmaceutical experts conducting research in the fields of stem cell biology, molecularaspects of stem cell research, tissue engineering, regenerative medicine, cellular therapy, OMICs, bioinformatics, and ethics.

Discusses almost all omics strategies relevant to stem cell and regenerative medicine Covers emerging bioinformatics to monitor pathological states of cancer and diseases management Contributors are expert researchers and physicians in the field

Autorentext
Babak Arjmand, M.D., Ph.D, was graduated from Iran University of Medical Sciences in medicine and received his Ph.D. degree in applied cell science from Tehran University of Medical Sciences, Tehran, Iran. He is currently Head and Director of Stem Cell and Regenerative Medicine Research Center, Endocrinology and Metabolism Cellular-Molecular Sciences Institute, Tehran University of Medical Sciences in Tehran, Iran. His research activities concern the development of cell- and gene-based clinical products through the translational pathway from the basic to the clinic focusing on GLP, GMP, and GCP standards.

Inhalt

Chapter 1: Trying to reveal the mysteries of stem cells using "omics" strategies.- Chapter 2: Genomics, Proteomics, and Metabolomics for Stem Cells Monitoring in Regenerative Medicine.- Chapter 3: Metabolic profiling of the Mesenchymal Stem Cells' Secretome.- Chapter 4: Different Gene Expression Profile of Mesenchymal Stem Cells from Various Sources.- Chapter 5: Genomic and Proteomic Monitoring of Stem Cell-Derived Exosomes.- Chapter 6: Proteomics Approaches Applied to Regenerative Medicine; Perspectives in stem cell Proteomics.- Chapter 7: Lipidomics of Adipogenic Differentiation of Mesenchymal Stem Cells.- Chapter 8: OMICs Profiling of Cancer Cells.- Chapter 9: Genomics, Proteomics and Metabolomics of Cancer Stem Cells (CSCs).- Chapter 10: From OMICs to Ethics, points to start the debate.- Index