Foodborne illnesses caused by various bacterial, viral, and fungal pathogens lead to a high number of morbidity and mortality in the U.S. and throughout the world. Recent advances in microbial genomics have significantly improved our understanding of the physiology, evolution, ecology, epidemiology, and pathogenesis of different foodborne pathogens. This book focuses on the genomics of foodborne bacterial pathogens. It begins with a brief overview of the recent advances in microbial genomics and the impact of genomics on food safety research. Then, eight chapters follow that elaborate some in-depth reviews on the genomics of several common foodborne bacterial pathogens including Bacillus, Campylobacter, Clostridium, Escherichia coli, Listeria, Salmonella, Staphylococcus, and Vibrio. Finally, the last four chapters focus on some current genomic, transcriptomic, and proteomic technologies and their applications in studying the epidemiology, evolution, and pathogenesis of foodborne bacterial pathogens. Genomics of Foodborne Bacterial Pathogens can be used as a reference by scientists and professionals in academia, government, and industry who are interested in understanding microbial genomics and using genomics tools to study foodborne bacterial pathogens. This book can also be used as a textbook for instructors and professors who teach food microbiology or microbial genomics-related courses at the post-graduate level.

One of the only books focusing on the genomics of foodborne bacterial pathogens - Includes in-depth reviews on the genomics of several common foodborne bacterial pathogens including Bacillus, Campylobacter, Clostridium, Escherichia coli, Listeria, Salmonella, Staphylococcus, and Vibrio Versatile book - excellent reference for scientists can also be used as a textbook at both the undergraduate and graduate level Includes supplementary material: sn.pub/extras

Autorentext
Wei Zhang received his Ph.D. degree from The University of Texas Graduate School of Biomedical Sciences. He joined the faculty of M. D. Anderson Cancer Center in 1994 where he is currently an Associate Professor and the Director of the Cancer Genomics Core Laboratory. Dr. Zhang's research programs include cancer genomics and informatics, tumor suppressor genes, and signal transduction studies. Dr. Zhang is an Associate Editor for American Association of Cancer Research journal Clinical Cancer Research, and serves on editorial board of journals Cancer Biology and Therapy, Histology and Histopathology, International Journal of Oncology, BMC Genomics, Technology in Cancer Research and Treatment, and Molecular Cancer.

Inhalt

1. Overview: The impact of microbial genomics on food safety.- 2. Genomics of bacillus species.- 3. Post genome analysis of the foodborne pathogen campylobacter jejuni.- 4. Genomics of clostridium.- 5. Genomics of escherichia and shigella.- 6. Listeria genomics.- 7. Genomics of salmonella species.- 8. Genomics of staphylococcus.- 9. Genomics of pathogenic vibrio species.- 10. Genomic and transcriptomic analyses of foodborne bacterial pathogens.- 11. Proteomics of foodborne bacterial pathogens.- 12. Molecular epidemiology of foodborne pathogens.- 13. The evolution of foodborne pathogens.- Index.