This paperback edition is a reprint of the 2000 edition. It provides comprehensive coverage of linear mixed models for continuous longitudinal data. Next to model formulation, it puts major emphasis on exploratory data analysis for all aspects of the model.

The SAS routines on mixed models have applications in many areas of statistics, especially biostatistics, but the procedures are not well- documented. Based on short courses given by the authors, this book provides practical guidance for SAS users.

Includes supplementary material: sn.pub/extras

Zusammenfassung
This paperback edition is a reprint of the 2000 edition. This book provides a comprehensive treatment of linear mixed models for continuous longitudinal data. Several variations to the conventional linear mixed model are discussed (a heterogeity model, conditional linear mixed models).

Inhalt
Examples.- A Model for Longitudinal Data.- Exploratory Data Analysis.- Estimation of the Marginal Model.- Inference for the Marginal Model.- Inference for the Random Effects.- Fitting Linear Mixed Models with SAS.- General Guidelines for Model Building.- Exploring Serial Correlation.- Local Influence for the Linear Mixed Model.- The Heterogeneity Model.- Conditional Linear Mixed Models.- Exploring Incomplete Data.- Joint Modeling of Measurements and Missingness.- Simple Missing Data Methods.- Selection Models.- Pattern-Mixture Models.- Sensitivity Analysis for Selection Models.- Sensitivity Analysis for Pattern-Mixture Models.- How Ignorable Is Missing At Random?.- The Expectation-Maximization Algorithm.- Design Considerations.- Case Studies.