This book gives a concise overview of the mathematical foundations of kinetics used in chemistry and systems biology. The analytical and numerical methods used to solve complex rate equations with the widely used deterministic approach will be described, with primary focus on practical aspects important in designing experimental studies and the evaluation of data. The introduction of personal computers transformed scientific attitudes in the last two decades considerably as computational power ceased to be a limiting factor. Despite this improvement, certain time-honored approximations in solving rate equations such as the pre-equilibrium or the steady-state approach are still valid and necessary as they concern the information content of measured kinetic traces. The book shows the role of these approximations in modern kinetics and will also describe some common misconceptions in this field.

Includes supplementary material: sn.pub/extras

Autorentext

Dr. Lajos Kovács University of Szeged Department of Medicinal Chemistry Dóm tér 8 6720 Szeged Hungary Dr. Dezs Csupor University of Szeged Institute of Pharmacognosy Eötvös u. 6 6720 Szeged Hungary Dr. Gábor Lente University of Debrecen Department of Inorganic and Analytical Chemistry Egyetem tér 1 4010 Debrecen Hungary Prof. Tamás Gunda University of Debrecen Department of Pharmaceutical Chemistry Egyetem tér 1 4010 Debrecen Hungary

Inhalt
Rates and Rate Equations.- Solving Rate Equations.- Inevitable Approximations.- Information from Parameter Values.- Common Pitfalls.