This is a fully revised Second Edition of a well-structured textbook that offers essential knowledge on the vascular system.

The reader will learn the properties, basic cellular mechanisms, and development of the different parts of the vascular system (including the heart and lung), gain knowledge on vascular and related diseases, and will be made familiar with common and most current methods and techniques applied to analyze the vascular system in patients, animal models, and ex vivo.

This book is based on a Ph.D. Course for students from various scientific backgrounds given at the Medical University of Vienna, and it will be a valuable resource for Master´s Students in vascular biology and biomedicine in general and a helpful tool for young researchers worldwide wishing to gain or refresh their knowledge in this field.

Basic principles on relevant diseases of the vascular system Methods relevant for the analysis of the vascular system in patients, in animal models and in vitro Basic information for PhD-students and young researchers, especially for those with a non-medical background

Autorentext
Prof. Dr. Margarethe Geiger was Deputy Head of the Center of Physiology and Pharmacology and Head of the Department of Vascular Biology and Thrombosis Research, Medical University of Vienna, Austria and Program Coordinator of the PhD Program Vascular Biology at the same Institution, currently she is retired.

Inhalt

1 . Morphological and Functional Characteristics of Blood and Lymphatic Vessels. Hantusch, B., Department of Pathology, Medical University of Vienna, Vienna, Austria.- 2 . The Heart: The Engine in the Center of the Vascular System. Demyanets, S., Department of Pathology, Medical University of Vienna, Vienna, Austria.- 3 . Regulation of Tissue Perfusion and Exchange of Solutes, Macromolecules, and Water Between Blood Vessels and the Interstitial Space. Salzmann, M., Department of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Wien, Austria. Schmid, D., Institute of Physiology, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria. Geiger, M., Department of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Wien, Austria.- 4 . Endothelial Cells: Function and Dysfunction. de Martin, R., Department of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.- 5 . Vascular Smooth Muscle Cells: Regulation of Vasoconstriction and Vasodilation. Wojta, J., Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria.- 6 . Embryonic Development of the Cardiovascular System. Wolfgang J. Weninger1 and Stefan H. Geyer, Division of Anatomy, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.- 7 . Cellular and Molecular Mechanisms of Vasculogenesis, Angiogenesis, and Lymphangiogenesis. Uhrin, P., Department of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.- 8 . Mechanisms of Hemostasis: Contributions of Platelets, Coagulation Factors, and the Vessel Wall. Mussbacher, M., Department of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria; Department of Pharmacology and Toxicology, Institute of Pharmaceutical Sciences, University of Graz, Graz, Austria. Kral-Pointner, J., Department of Internal Medicine II/ Division of Cardiology, Medical University of Vienna, Austria; Salzmann, M., Department of Internal Medicine II/ Division of Cardiology, Medical University of Vienna, Austria. Schrottmaier, W., Department of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria. Assinger, A., Department of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.- 9 . Biologically Active Lipids in Vascular Biology. Upchurch, C., Leitinger, N., Department of Pharmacology and Robert M. Berne Cardiovascular Research Center, University of Virginia.- 10 . Atherosclerosis. Mayer, F., Innerhofer, R., Koller, T., Binder, C., Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.- 11 . Venous Thromboembolism. Gary, T., Clinical Department of Angiology, University of Graz, Graz, Austria.- 12 . Pulmonary vascular diseases. Ondracek, A., Department of Internal Medicine II, Division of Cardiology, Center of Cardiovascular Medicine, Medical University of Vienna, Vienna, Austria. Dorfmüller, P., Department of Pathology, Universities of Giessen and Marburg Lung Center (UGMLC), Justus-Liebig University, Germany. Lang, I., Department of Internal Medicine II, Division of Cardiology, Center of Cardiovascular Medicine, Medical University of Vienna, Vienna, Austria.- 13 . Genetics of Vascular Diseases. Mannhalter, C., Medical University Vienna, Vienna, Austria.- 14 . Animal Models in Cardio-vascular Biology. Rohringer, S., Bergmeister, H., Hamza, O., Kiss, A., Nagel, F., Pilz, P., Plasenzotti, R., Podesser, B., Ludwig Boltzmann Cluster for Cardiovascular Research at the Center for Biomedical Research and Translational Surgery, Medical University of Vienna, Austria.- 15 . Endothelial Cell Isolation and Manipulation. Brostjan, C., Department of General Surgery, Medical University of Vienna, Vienna, Austria.- 16 . In Vitro Assays Used to Analyse Vascular Cell Functions. Kirchhoff, A., Department of Orthopaedics & Trauma Surgery, Diakonissenkrankenhaus Leipzig, Teaching Hospital of the University of Leipzig, Leipzig, Germany. Wechselberger, C., Division of Pathophysiology, Institute of Physiology and Pathophysiology, Medical Faculty, Johannes-Kepler-University Linz, Austria. Bernhard, D., Division of Pathophysiology, Institute of Physiology and Pathophysiology, Medical Faculty, Johannes-Kepler-University Linz, Austria; Clinical Research Institute for Cardiovascular and Metabolic Diseases, Medical Faculty, Johannes-Kepler-University Linz, Austria. Messner, B., Cardiac Surgery Research Laboratory, Department of Cardiac Surgery, Medical University of Vienna, Austria.- 17 . The Porcine Coronary Artery Ring Myograph System. Schmid, D., Institute of Physiology, Medical University of Vienna, Austria. Hofbauer, T., Department of Cardiology, Internal Medicine II, Medical University of Vienna, Austria.- 18 . Proteomics in Vascular Biology. Zellner, M., Institute of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria. Resch, U., Institute of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria. Umlauf, E., Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria. Miller, I., Institute of Medical Biochemistry, Department of Biomedical Sciences, University of Veterinary Medicine Vienna.