Experimental and Theoretical Advances in Biological Pattern Formation

This volume contains the proceedings of the NATO ARW on 'Biological Pattern Formation' held at Merton College, University of Oxford, on 27-31 August, 1992. The objective of the workshop was to bring together a select group of theoreticians and experimental biologists to present the latest results in the area of biological pattern formation and to foster interactiqn across dis- plines. The workshop was divided into 5 main areas: (i) limb development, (ii) Dictyostelium discoideum, (iii) Drosophila, (iv) cell movement, (v) g- eral pattern formation. We thank all the participants for their contributions, enthusiasm, and willingness to collaborate. There was a genuine, open, and extremely fru- ful interaction between the experimentalists and theoreticians which made the workshop a success. We also thank The Welcome Trust for providing additional funding. The local organization fell mainly on Denise McKittrick and Beverley Bhaskhare at the Mathematical Institute, Oxford, and Jeanette Hudson and the staff of Merton College. We greatly appreciate their help and patience. We also thank Jonathan Sherratt, Wendy Brandts and Debbie Benson for helping out in the conference and for providing a happy welcome to parti- pants on a typically cold, wet and windy English summer day.

Klappentext

Proceedings of a NATO ARW held in Oxford, United Kingdom, August 27-31, 1992

Zusammenfassung
Proceedings of a NATO ARW held in Oxford, United Kingdom, August 27-31, 1992

Inhalt

1. General Models of Pattern Formation: Some Uses, Problems and Successes.- 2. Process and Outcome: Evolutionary Analysis of Morphological Patterns.- 3. Retinoic Acid Cannot Be the Morphogen in Reaction-Diffusion Models for the Formation of the Chick Wing Bud.- 4. Pattern Formation in Heterogeneous Domains.- 5. A Field Model of Symmetry Reversals in the Pattern Regulation of a Cell.- 6. Patterning in Limbs: The Resolution of Positional Confrontations.- 7. The Development of a Spatial Pattern in a Model for Cancer Growth.- 8. Sequential and Synchronous Skin Pattern Formation.- 9. Control of Gap Junction Permeability Can Control Pattern Formation in Limb Development.- 10. Wave Patterns in One-Dimensional Nonlinear Degenerate Diffusion Equations.- 11. Mapping Gene Activities into Morphological Patterns in Drosophila.- 12. Trajectories of Swimming Micro-Organisms and Continuum Models of Bioconvection.- 13. Testing the Theoretical Models for Limb Patterning.- 14. The Chicken and the Egg.- 15. Supercomputer Simulation of Turing Structures in Drosophila Morphogenesis.- 16. The Role of Hox Genes in Axis Specification.- 17. Looking at Early Development in Xenopus laevis Using NMR Micro-Imaging.- 18. Mechanism of Local Chaos in Active Distributed Media.- 19. Patterns Formed through Cell-Cell Interactions: Spontaneous Selection of Dominant Directions.- 20. Controlling Reaction-Diffusion Pattern with Gradients: Lessons from Drosophila, and Trajectories through Parameter Space.- 21. Steady-State Patterns in a Reaction Diffusion System with Mixed Boundary Conditions.- 22. Pattern Control in Hydra: Basic Experiments and Concepts.- 23. Predicted and Observed Spatial Prepatterns in (Hair) Wool Follicle Bulbs.- 24. The Speed of a Brownian Ratchet.- 25. Oscillations and Waves in a Model of InsP3-Controlled Calcium Dynamics.- 26. Four Signals to Shape a Slime Mold.- 27. Modelling Actin Filament Alignment.- 28. The Motile Behavior of Amoebae in the Aggregation Wave in Dictyostelium discoideum.- 29. Retinoic Acid: An Autocatalytic Morphogen.- 30. The Hardware and Software of Morphogenesis: Studies with the Dictyostelium discoideum Slug, a Simple Tissue.- 31. Factors Controlling the Directionality of Mesoderm Cell Migration in the Xenopus Gastrula.- 32. Analysis and Modelling of the Organization of the Mammalian Cerebral Cortex.