Now in a revised second edition, this book is a comprehensive guide to teach surgeons, surgical fellows and surgical residents, regardless of their specialty, the skills to appraise what they encounter in the surgical literature. Surgeons need to be able to understand what they read before applying the conclusions of a surgical article to their practice. As most surgeons do not have the extra training in health research methodology, understanding how the research was done, how to interpret the results, and finally deciding to apply them to the patient level can be a difficult task.

Chapters included here explain the methodological issues pertaining to the various study designs reported in the surgical literature. Readers are taught how to search the literature for the best evidence that will answer the surgical problem under discussion. An identified article that seems relevant to the problem under investigation can be appraised by addressing three key questions: 1) Is the study I am reading valid? 2) what are the results of this study? and 3) can I apply these results to my patients? Chapters new to this edition discuss cluster RCTs, network meta-analyses, enhanced recovery after surgery (ERAS) and core outcome sets (COS).

While the primary goal of Evidence-Based Surgery is to teach surgeons how to appraise the surgical literature, an added benefit is that the concepts explained here may help research-minded surgeons produce higher quality research.

A comprehensive guide to how to critically review, appraise and interpret the surgical literature Discusses the evidence hierarchy, research design and methodology, statistics and much more An excellent resource for practicing surgeons at every level of experience

Autorentext

Achilles Thoma, MD, MSc, FRCSC, FACS

Department of Surgery, Division of Plastic Surgery, McMaster University, Hamilton ON, Canada

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada

Sheila Sprague, PhD

Department of Surgery, Division of Orthopaedic Surgery, McMaster University, Hamilton ON, Canada

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada

Sophocles H. Voineskos, MD, MSc, FRCSC

Division of Plastic, Reconstructive, and Aesthetic Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada

Li Ka Shing Knowledge Institute, Unity Health, Toronto, ON, Canada

Pablo E. Serrano, MD, PhD, MPH, FACS, DABS

Department of Surgery, Hepatobilliary and Pancreatic Surgical Oncology, McMaster University, Hamilton, ON, Canada.

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada

Charles H. Goldsmith, PhD

Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada

Inhalt

History of Evidence-Based Surgery (EBS).- The Steps of Practicing Evidence-Based Surgery (EBS).- Developing a Surgical Clinical Research Question: To Find the Answer in Literature Search or in Pursuing Clinical Research.- Finding the Evidence Through Searching the Literature.- Hierarchy of Evidence in Surgical Research.- Evaluating Surgical Interventions.- A Primer on Outcome Measures for Surgical Interventions.- Patient-Reported Outcome Measures in Surgical Care.- Surrogate Endpoints.- How to Asses an Article that Deals with Health-Related Quality of Life.- Randomized Controlled Trial Comparing Surgical Interventions.- How to Assess a Pilot Trial in Surgery.- Non-Inferiority Randomized Controlled Trials.- Expertise-Based Randomized Controlled Trials.- Cluset Randomized Trials in Surgery.- The Surgeon's Guide to Systematic Review and Meta-Analysis.- Prospective and Retrospective Cohort Studies.- Case-Control Studies.- Evaluating Case Series in Surgery.- Quality Improvement and Patient Safety in Surgery.- Diagnostic Studies in Surgery.- How to Assess a Prognostic Study.- Decision Analysis and Surgery.- Economic Evaluations in Surgery.- Studies Reporting Harm in Surgery.- Evaluating Surveys and Questionnaires in Surgical Research.- Simple Statistical Tests and P Values.- Confidence Intervals.- Power and Sample Size.- Subgroup Analyses in Surgery.- Surgical Guideline Appraisal.- Network Meta-Analyses in Surgical Trials.- Enhanced Recovery After Surgery (ERAS).- Core Outcome Sets.