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The Symposium "Esophageal Carcinoma - State of the Art" has aroused very great interest. The numerous enquiries have caused us to publish the congress proceedings in the present volume. Particular attention was paid to current topical problems. One of the areas on which the present volume focuses is the epidemiol ogy and pathology of esophageal adenocarcinoma. Compared to squamous epithelial carcinoma, this is increasing in incidence in Europe. Modern diagnostic methods are described such as laser induced fluorescence spectroscopy or the optical coherence endo scopic technique. The latter enables normal mucosa to be distin guished from dysplastic or malignant lesions, in contrast to con ventional endoscopy. As in other tumors of the gastrointestinal tract, neoadjuvant therapy is becoming of increasing importance. Since the indication crucially depends on the tumor stage, two contributions deal with postoperative staging, with the diagnostic reliability of the individual techniques and new methods such as endoluminal MRI. There is no doubt that neoadjuvant chemo therapy is indicated in tumors which are irresectable and in tumor stages in which resectability is uncertain. However, to what extent it should also be applied in the resectable stage will be discussed in the individual contributions both for adenocarci noma and for squamous epithelial carcinoma. In the meantime, surgical treatment of esophageal carcinoma has been largely stan dardized. Differences with regard to radicality are still found in the extent of lymphadenectomy, especially in inclusion of cervi cal lymph nodes.
Includes supplementary material: sn.pub/extras
Klappentext
This volume presents an overview of the current state of knowledge in the diagnosis, classification, surgical and multimodality therapy of malignant esophageal tumors. This includes squamous cell carcinoma as well as adenocarcinoma and in particular Barret's syndrome. The chapters focus on new diagnostic procedures such as laser fluorescence spectroscopy, chromoscopy and magnification endoscopy. These procedures not only help to optimize tumor staging but also form a basis for making noninvasive surgical and interventional methods safer and more effective. Since the results of treatment of malignant esophageal tumors are often still unsatisfactory, development of combined therapies directed at improving the prognosis become just as significant as new operation techniques. This volume, characterized by its multidisciplinarity and variety of approaches to the topic, shows how the prevailing limitations in the management of this tumor entity can be overcome in the future.
Inhalt
Epidemiology of Esophageal Cancer, Especially Adenocarcinoma of the Esophagus and Esophagogastric Junction.- Modern Pathology: Prognostic Parameters in Squamous Cell Carcinoma of the Esophagus.- Malignant Progression in Barrett's Esophagus: Pathology and Molecular Biology.- Malignant Degeneration of Barrett's Esophagus: Clinical Point of View.- New Diagnostic Methods for Esophageal Carcinoma.- Esophageal Carcinoma: Current Staging Strategies.- What's New in Imaging? New Magnetic Resonance Imaging of Esophageal Cancer Using an Endoluminal Surface Coil and Antibody-Coated Magnetite Particles.- Risk Analysis in Esophageal Surgery.- Neoadjuvant Chemoradiation Followed by Surgery for Resectable Esophageal Cancer.- Neoadjuvant Therapy of Squamous Cell Carcinoma of the Esophagus.- Therapy of Cervical Esophageal Carcinoma.- Esophageal Cancer: A European Perspective.- Significance of Extended Systemic Lymph Node Dissection for Thoracic Esophageal Carcinoma in Japan.- Gastric Conditioning.- Fundus Rotation Gastroplasty: A Modified Gastric Tube.- Colon Interposition.- Complications Following Esophageal Surgery.- Photodynamic Therapy.- Endoscopic Mucosectomy: An Alternative Treatment for Superficial Esophageal Cancer.- Quality of Life in Patients with Oesophageal Cancer.