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The gold standard of neuroscience texts-updated with hundreds of brand-new images and fully revised content in every chapter**

*A Doody's Core Titles for 2024 & 2023! *

For more than 40 years, Principles of Neural Science has helped readers understand the link between the human brain and behavior. As the renowned text has shown, all behavior is an expression of neural activity and the future of both clinical neurology and psychiatry is dependent on the progress of neural science. Fully updated, this sixth edition of the landmark reference reflects the latest research, clinical perspectives, and advances in the field. It offers an unparalleled perspective on the the current state and future of neural science.
This new edition features:

• Unmatched coverage of how the nerves, brain, and mind function
• NEW chapters on:
• The Computational Bases of Neural Circuits that Mediate Behavior
• Brain-Machine Interfaces
• Decision-Making and Consciousness
• NEW section on the neuroscientific principles underlying the disorders of the nervous system
• Expanded coverage of the different forms of human memory
• Highly detailed chapters on stroke, Parkinson's disease, and multiple sclerosis

• 2,200 images, including 300 new color illustrations, diagrams, radiology studies, and PET scansPrinciples of Neural Science, Sixth Edition benefits from a cohesive organization, beginning with an insightful overview of the interrelationships between the brain, nervous system, genes, and behavior.

  The text is divided into nine sections:

  Part I: Overall Perspective provides an overview of the broad themes of neural science, including the basic anatomical organization of the nervous system and the genetic bases of nervous system function and behavior.

  Part II: Cell and Molecular Biology of Cells of the Nervous System examines the basic properties of nerve cells, including the generation and conduction of propagated signaling.

  Part III: Synaptic Transmission focuses on the electrophysiological and molecular mechanism of synaptic transmission with chapters on neuronal excitability, neurotransmitters, and transmitter release.

  Part IV: Perception discusses the various aspects of sensory perception, including how information from the primary organs of sensation is transmitted to and processed by the central nervous system.

  Part V: Movement considers the neural mechanisms underlying movement and examines a new treatment that addresses how the basal ganglia regulate the selection of motor actions and instantiate reinforcement learning.

  Part VI: The Biology of Emotion, Motivation and Homeostasis examines the neural mechanisms by which subcortical areas mediate homeostatic control mechanisms, emotions, and motivation.

  Part VII: Development and the Emergence of Behavior looks at the nervous system from early embryonic differentiation to the formation and elimination of synapses.

  Part VIII: Learning, Memory, Language and Cognition expands on the previous section, examining the cellular mechanisms of implicit and explicit memory storage, as well as decision-making and consciousness.

  Part IX: explores the neural mechanisms underlying diseases and disorders of the nervous system, including autism spectrum disorder, epilepsy, schizophrenia, and anxiety.

  Inhalt

  Part I: Overall Perspective
  Chapter 1: The Brain and Behavior
  Chapter 2: Genes and Behavior
  Chapter 3: Nerve Cells, Neural Circuitry, and Behavior
  Chapter 4: The Neuroanatomical Bases by Which Neural Circuits Mediate Behavior
  Chapter 5: The Computational Bases of Neural Circuits That Mediate Behavior
  Chapter 6: Imaging and Behavior

  Part II: Cell and Molecular Biology of Cells of the Nervous System
  Chapter 7: The Cells of the Nervous System
  Chapter 8: Ion Channels
  Chapter 9: Membrane Potential and the Passive Electrical Properties of the Neuron
  Chapter 10: Propagated Signaling: The Action Potential

  Part III: Synaptic Transmission
  Chapter 11: Overview of Synaptic Transmission
  Chapter 12: Directly Gated Transmission: The Nerve-Muscle Synapse
  Chapter 13: Synaptic Integration in the Central Nervous System
  Chapter 14: Modulation of Synaptic Transmission and Neuronal Excitability: Second Messengers
  Chapter 15: Transmitter Release
  Chapter 16: Neurotransmitters

  Part IV: Perception
  Chapter 17: Sensory Coding
  Chapter 18: Receptors of the Somatosensory System
  Chapter 19: Touch
  Chapter 20: Pain
  Chapter 21: The Constructive Nature of Visual Processing
  Chapter 22: Low-Level Visual Processing: The Retina
  Chapter 23: Intermediate-Level Visual Processing and Visual Primitives
  Chapter 24: High-Level Visual Processing: From Vision to Cognition
  Chapter 25: Visual Processing for Attention and Action
  Chapter 26: Auditory Processing by the Cochlea
  Chapter 27: The Vestibular System
  Chapter 28: Auditory Processing by the Central Nervous System
  Chapter 29: Smell and Taste: The Chemical Senses

  Part V: Movement
  Chapter 30: Principles of Sensorimotor Control
  Chapter 31: The Motor Unit and Muscle Action
  Chapter 32: Sensory-Motor Integration in the Spinal Cord
  Chapter 33: Locomotion
  Chapter 34: Voluntary Movement: Motor Cortices
  Chapter 35: The Control of Gaze
  Chapter 36: Posture
  Chapter 37: The Cerebellum
  Chapter 38: The Basal Ganglia
  Chapter 39: Brain-Machine Interfaces

  Part VI: The Biology of Emotion, Motivation, and Homeostasis
  Chapter 40: The Brain Stem
  Chapter 41: The Hypothalamus: Autonomic, Hormonal, and Behavioral Control of Survival
  Chapter 42: Emotion
  Chapter 43: Motivation, Reward, and Addictive States
  Chapter 44: Sleep and Wakefulness

  Part VII: Development and the Emergence of Behavior
  Chapter 45: Patterning the Nervous System
  Chapter 46: Differentiation and Survival of Nerve Cells
  Chapter 47: The Growth and Guidance of Axons
  Chapter 48: Formation and Elimination of Synapses
  Chapter 49: Experience and the Refinement of Synaptic Connections
  Chapter 50: Repairing the Damaged Brain
  Chapter 51: Sexual Differentiation of the Nervous System

  Part VIII: Learning, Memory, Language and Cognition
  Chapter 52: Learning and Memory
  Chapter 53: Cellular Mechanisms of Implicit Memory Storage and the Biological Basis of Individuality
  Chapter 54: The Hippocampus and the Neural Basis of Explicit Memory Storage
  Chapter 55: Language
  Chapter 56: Decision-Making and Consciousness

  Part IX: Diseases of the Nervous System
  Chapter 57: Diseases of the Peripheral Nerve and Motor Unit
  Chapter 58: Seizures and Epilepsy
  Chapter 59: Disorders of Conscious and Unconscious Mental Processes
  Chapter 60: Disorders of Thought and Volition in Schizophrenia
  Chapter 61: Disorders of Mood and Anxiety
  Chapter 62: Disorders Affecting Social Cognition: Autism Spectrum Disorder
  Chapter 63: Genetic Mechanisms in Neurodegenerative Diseases of the Nervous System
  Chapter 64: The Aging Brain