Starting in 1986, the European School of Oncology has expanded its activities in postgraduate teaching, which consisted mainly of traditional disease-orientated courses, by promoting new educational initiatives. One of these is the cloister seminars, short meetings intended for highly qualified oncologists and dealing with specific, controversial aspects of clinical practice and research. Another is the institution of permanent study groups, also called task forces, where a limited number of leading experts are invited to meet once a year with the aim of defining the state of the art and possibly reaching a consensus on developments and treatment in specific fields of oncology. This series of ESO Monographs was designed with the specific purpose of disseminating the results of the most interesting of the seminars and study groups, and providing concise and updated reviews of the subjects discussed. It was decided to keep the layout very simple in order to keep costs to a minimum and make the monographs available in the shortest possible time, thus overcoming a common problem in medical literature: that of the material being outdated even before publication. Umberto Veronesi Chairman, Scientific Committee European School of Oncology Table of Contents How to Read this Monograph F.CAvALLI ......... . 1 Experimental Strategies for Studying the Development of Breast Cancer with Special Reference to Steroid Hormones, Growth Factors and Oncogenes R.J.B. KING . . . . . . . . . . . . . . . . . . . . . . . . .. . . . 5 . . .

Autorentext
Franco Cavalli, geboren 1942, ist Chefarzt fur Onkologie in Bellinzona und Professor an den Universitäten Bern und Varese. 1989 grundete er die internationale Fachzeitschrift Annals of Oncology (hrsg. von der Universität Oxford), die er zehn Jahre lang als Chefredaktor fuhrte. Cavalli hat zahlreiche internationale Auszeichnungen erhalten, darunter den Ehrenpreis der North Down Development Organization (NDDO). Er war Präsident der Krebsliga Schweiz, seit 2003 ist er wissenschaftlicher Direktor des Onkologischen Instituts der italienischsprachigen Schweiz (IOSI) in Bellinzona, 2006 wurde er Präsident der Internationalen Krebs-Union (UICC). Er ist einer der renommiertesten Krebsforscher in Europa. Zudem ist er Mitbegrunder der Organisation fur Medizinische Hilfe fur Zentralamerika und hat mehrere Projekte in Nicaragua, El Salvador, Guatemala und Mexiko initiiert. Cavalli ist auch politisch aktiv, er war Fraktionschef der SP im Bundesparlament in Bern.

Inhalt
How to Read this Monograph.- Experimental Strategies for Studying the Development of Breast Cancer with Special Reference to Steroid Hormones, Growth Factors and Oncogenes.- Steroids, Growth Factors and Oncogenes in Breast Cancer.- Oestrogen and Anti-Oestrogen Action: A Hypothesis for the Regulation of Breast Cancer Cell Replication.- Methodology of Clinical Trials. Investigating Endocrine Mechanisms in Breast Cancer.- Endocrine Treatment of Advanced Breast Cancer.- Endocrine Aspects in Adjuvant Therapy for Early Breast Cancer.- Towards an Optimal Strategy for the Adjuvant Therapy of Breast Cancer.- Tamoxifen Prophylaxis: Prevention is Better Than Cure - Prevention is Cure?.