The Encyclopedia of Biophysics is envisioned both as an easily accessible source of information and as an introductory guide to the scientific literature. It includes entries describing both Techniques and Systems. In the Techniques entries, each of the wide range of methods which fall under the heading of Biophysics are explained in detail, together with the value and the limitations of the information each provides. Techniques covered range from diffraction (X-ray, electron and neutron) through a wide range of spectroscopic methods (X-ray, optical, EPR, NMR) to imaging (from electron microscopy to live cell imaging and MRI), as well as computational and simulation approaches.In the Systems entries, biophysical approaches to specific biological systems or problems from protein and nucleic acid structure to membranes, ion channels and receptors are described. These sections, which place emphasis on the integration of the different techniques, therefore provide an inroadinto Biophysics from a biological more than from a technique-oriented physical/chemical perspective. Thus the Encyclopedia is intended to provide a resource both for biophysicists interested in methods beyond those used in their immediate sub-discipline and for those readers who are approaching biophysics from either a physical or biological background.

First ever comprehensive encyclopedia of biophysics of this size Covering all field of modern biophysics Online version with extensive cross-referencing / hyperlinks Published in cooperation with the European Biophysical Societies' Association (EBSA)

Autorentext
Prof. Gordon Robert's Career:

• PhD, University of London, 1967.
• Merck, Sharp & Dohme, New Jersey, 1967-1969.
• MRC Molecular Pharmacology Unit, Cambridge, 1969-1972.
• National Institute for Medical Research, London, 1972-1986.
• Joined staff of Department of Biochemistry, 1986.
• Head of Department 2000-2004.
• Director of Henry Wellcome Laboratories of Structural Biology.
• Head of School of Biological Sciences, 2004-2008.
• Honorary Professor, 2008-present
  For more information please visit: http://www2.le.ac.uk/departments/biochemistry/staff/roberts.

Inhalt

• Proteins

  • Protein Structure
  • Protein Folding
  • Protein Dynamics

• DNA and RNA

• Carbohydrates

• Macromolecular complexes

  • Protein-Protein interactions
  • Protein-nucleic acid interactions

• Mechanoenzymes

  • Motors: myosin, kinesin & dynein
  • Rotary motors
  • Motor proteins on nucleic acids

• Membrane biophysics

  • Lipids
  • Proteins

• Electron transfer

• Ion Channels

• Receptors

• Transporters

• Biomaterials & Biosensors

• Diffraction methods

• NMR

  • Solution state NMR
  • Solid state NMR

• EPR

  • Metalloprotein EPR
  • Spin-label EPR<

• Optical spectroscopy

  • Circular dichroism & related techniques
  • UV/visible absorption spectroscopy
  • Fluorescence
  • Vibrational spectroscopy

• X-ray spectroscopy

• Single molecule methods

• Computational Biophysics

  • Structure prediction & modeling
  • Molecular dynamics simulation
  • Computational studies of enzyme mechanisms

• Thermodynamics

• Kinetics

• Mass spectrometry

• Molecular shape & hydrodynamics

• Electron microscopy

• Live cell & in vivo imaging

  • Fluorescence imaging
  • MRI & PET imaging

• Cell biophysics