Proteomics is a well-established area of Science; yet with a strong area in constant evolution, namely sample treatment. There few books that currently cover the field of emerging sample treatments in proteomics, this new volume will be the first to cover all emerging and existing studies.

This unique book presents the latest advances in the field focusing on emerging trends linked to high-resolution mass spectrometry, technology addressed to treat samples faster and to attempts to simplify the proteome for the reader.

Focuses on nanotechnology and label free quantification as the ultimate way to handle samples Attempts to simplify the proteome for the reader This book's approach is based in the latest technical advances, while still outlining the classic approaches

Autorentext

Dr. J. L. Capelo is co-head of the bioscopegroup (www.bioscopegroup.org) and his CV comprises (up to December 2018): 224 manuscripts; 205 congress communications (orals and posters); 23 projects; 2 Patents, 1 license agreement and 1 book. He has chaired 39 international conferences and presently is involved in the direction of 7. He was member of the advisory board of Talanta from 2006 to 2014, and he is Editor in Chief of the on-line Journal JIOMICS (www.JIOMICS.com) since its creation in 2011. He is presently mentoring or co-mentoring a total of seven doctoral theses and he has mentored 3 post-doctoral grants, 10 doctoral grants, 9 masters and 8 final projects. His current research interest is devoted to developing new methodological approaches in biomarker discovery using nanoparticles and new proteomics approaches to unravel bacterial resistance to antibiotics. He is Fellow Member of the Royal Society of Chemistry and member of the Portuguese Society of Chemistry.

Inhalt

Ch:1-Proteomics: Tools of the Trade.- Ch:2-Sample treatment for Saliva proteomics.- Ch:3-MS-based proteomic analysis of serum and plasma problem of high abundant components; lights and shadows of albumin removal.- Ch:4-Sample Treatment for tissue proteomics in Cancer, Toxicology and Forensics.- Ch:5-Sample treatment for urine proteomics.- Ch:6-A method for comprehensive proteomic analysis of human faecal samples to investigate gut dysbiosis in patients with cystic fibrosis.- Ch:7-Sample Preparation Focusing on Plant Omics.- Ch:8-Metaproteomics: Sample Preparation and Methodological Considerations.