Biochips incorporate a verity of means including electronic, photonic and microfluidic devices; biological materials (living cells, tissue, enzymes, nucleic acid and etc.) and chemical analysis to produce the detectable signals for identification of biological phenomena. Among several competing biochip technologies, Complementary Metal Oxide Semiconductor (CMOS) process offers the advantages of low cost, integrated, high precision and portable techniques suitable for point-of-care diagnostics.

Advanced CMOS Biochip takes multi-path approach: microelectronic design and implementation of bio-interfaces offering a vital contemporary view of a wide range of integrated circuits and system for electrical, magnetic, optical and mechanical sensing and actuating blocks and much more; classical knowledge of biology, biochemistry as well as microfluidics. The coverage is both practical and in depth integrating experimental, theoretical and simulation examples. By using Advanced CMOS Biochip , readers will have the fundamentals and design techniques to grasp the situation which arise typically in CMOS biochip devices.

Offers a complete overview of CMOS designers who are interested in the design and fabrication of biochips CMOS Biochip is very new approach and not many books have been published in the area A unique multidisciplinary book which provides a broad overview of the emerging field of CMOS biochips

Autorentext

Ebrahim Ghafar-Zadeh received the BSc and MSc degrees in Electrical Engineering from KNT and Tehran Universities, Tehran, Iran, in 1992 and 1994, respectively. In 1994 he joints the electrical engineering department at SCU University, Ahvaz, Iran as faculty memeber. During 2004-2008, he pursued a PhD degree in electrical engineering at Ecole Polytechnique de Montreal, Canada. In January 2008 and September 2008, he received two fellowship award from NSERC Canada and ReSMiQ Quebec, Canada which allowed him to continue his research for fully integrated bacteria detection. The research interests of Dr. Ghafar-zadeh include the circuit and system design, implementation and packaging technologies for lab-on-chip applications. Mohamad Sawan received his BSc in Electrical Engineering from Université Laval (1984), and MSc (1986) and PhD (1990) both in Electrical Engineering from Université de Sherbrooke. He then completed post-doctoral training at Montréal's McGill University in 1991, and in that same year, joined École Polytechnique de Montréal, where he is currently a Professor of Microelectronics. Dr. Sawan's scientific interests focus on the design and testing of mixed-signal (analog, digital and RF) circuits and systems; digital and analog signal processing; and the modelling, design, integration, assembly and validation of advanced wirelessly powered and controlled monitoring and measurement techniques. These topics are oriented toward biomedical implantable devices and telecommunications applications. Dr. Sawan is holder of the Canada Research Chair in Smart Medical Devices. He heads the Microsystems Strategic Alliance of Québec - ReSMiQ and is founder of the Eastern Canada Chapter of the IEEE-Solid State Circuits Society. He also founded the International IEEE-NEWCAS conference, co-founded the International Functional Electrical Stimulation Society, and founded the Polystim Neurotechnologies Laboratoryat Ecole Polytechnique. He is the editor of Springer mixed-signal letters, Chair of the IEEE Biomedical CAS (BioCAS) Technical Committee, and member of the Biotechnology Council representing the IEEE-CAS Society. He has been awarded seven patents. He received the Barbara Turnbull Award for spinal cord research, the Medal of Merit from the Lebanese President (2005), and the J.-A. Bombardier Award from the Association Francophone pour le savoir (ACFAS). Dr. Sawan is a Fellow of both the Canadian Academy of Engineering and the IEEE.

Inhalt
Promises of CMOS technology for biological applications.- Fundamental of Chemo-and bio-interfaces.- Electro-Microfluidics.- Integrated front-end devices.- Biochip circuit designs.- Micro-and nanofabrication post-processing methods.- Current and Emerging CMOS Technologies.