Autorentext

Dominique Meynial-Denis, PhD, studied Biochemistry and Molecular Biology at the University Paul Sabatier of Toulouse, France and earned her PhD on intermolecular interactions between drug and plasma proteins followed by magnetic resonance spectroscopy (MRS) at the same university in 1985. Since 1986, she worked as a scientist at the National Institute of Agricultural Research (INRA) in Clermont-Ferrand in a Department focusing on Human Nutrition. Consequently, she became a Nutritionist and specialized her research on Sarcopenia and Aging in 1994. She applied MRS to metabolic pathways of amino acids in muscle during aging. Dr. Meynial-Denis earned a second PhD in 1998 on amino acid fluxes throughout skeletal muscle during aging. She was mainly interested in the effect of glutamine supplementation in advanced age. She was a member of the French Society of Enteral and Parenteral Nutrition (SFNEP), of the European Society of Clinical Nutrition and Metabolism (ESPEN) and of the International Association of Gerontology and Geriatrics (IAGG). She was a regular reviewer for various international nutrition journals.

Klappentext

What if you could understand the intricate mechanisms that control how our cells age-and learn how to combat them? Cellular Aging and Consequences in Humans: Nutritional and Clinical Studies delivers a comprehensive exploration of cellular senescence and cutting-edge anti-aging strategies that may hold the key to healthier aging.

From the fundamental processes driving cellular aging to tissue-specific developments, this authoritative resource examines:

• The complex interplay between aging and disease
• Breakthrough research on senescence across different human tissues
• Revolutionary insights into age-related disorders
• Cutting-edge physiologic, cellular, molecular, and genetic studies Whether you're a researcher, healthcare professional, or student, this essential reference provides the tools to understand-and potentially influence-the biology of aging at its most fundamental level. Expertly organized and thoroughly researched, it bridges the gap between theoretical concepts and practical applications in the field of cellular aging.

Advance your understanding of one of medicine's most compelling frontiers and discover how new insights into cellular senescence could transform our approach to aging and age-related diseases.

Inhalt

Chapter 1 - The role of epigenetic regulation in senescence and its implication in aging.

Chapter 2 - Telomeres and age-related diseases

Chapter 3 - Immune dysregulation and skeletal muscle regenerative failure in aging

Chapter 4 - Potential therapeutic agents targeting senescent cells and their influence on various organs and tissues

Chapter 5 - Prevention and Management of Aging Skin

Chapter 6 - Age-associated Changes in Different Cell Types in the Brain.

Chapter 7 - Stress, Neuronal Senescence and Brain Aging

Chapter 8 - Adjusting neuronal proteostasis to control life and health span

Chapter 9 - Cellular Changes in Age-Related Hearing Loss

Chapter 10 - Age-related Cardiac Pathologies

Chapter 11 - Cell senescence in kidney aging and in kidney disease

Chapter 12 - Cellular and molecular mechanisms contributing to senescence in sarcopenia

Chapter 13 - Cellular senescence and skeletal muscle aging: Defining the role of essential amino acids

Chapter 14 - Molecular mechanism of age-related disorder of skeletal muscle (sarcopenia)

Chapter 15 - Stem cell aging and senescence in skeletal muscle

Chapter 16 - The role of vitamin D in telomere biology

Chapter 17 - Dysphagia and the attenuating approach for aging and related disorders

Chapter 18 - The role of cellular senescence in tumorigenesis during aging

Chapter 19 - Rejuvenating Immunity with Aging: A Panacea for Carcinogenesis in Elderly Population