Diagnosis of Mycotoxicoses

Current problems associated with the mycotoxicoses include the recognition of an animal disease as being a mycotoxicosis and confirmation of diagnosis of the mycotoxicosis by satisfactory laboratory methods. By gathering a vast amount of scientific literature, diagnosticians can provide themselves with suitable informa tion for making such a diagnosis. However, the increased number of reported intoxications caused by fungi, the wide range in diversity of disease conditions and the chemical compounds causing the mycotoxicoses, and the ever-changing and rapid developments in the technology of mycotoxin analysis has made the gathering and assimilation of sufficient information by the diagnostician an insurmountable task. This is the reason for development of the symposium and the publication of this book; the first time that the subject of diagnosis of mycotoxicoses has been assembled in a single publication and as a compilation of topic papers by experts in this subject area. The UJNR panel on toxic microorganisms is interested in all aspects of intox ications by microorganisms as evidenced by its annual joint meetings in either the United States or Japan and its involvement in sponsoring numerous symposia and several publications in this broad scientific area. The overall mission of the National Animal Disease Center includes research efforts in the improvement or establishment of diagnostic methods for animal diseases. The UJNR panel and the NADC provided the funds and encouragement for the development of a symposium on the diagnosis of mycotoxicoses in the United States and . Tapan.

Klappentext

Symposium on the Diagnosis of Mycotoxicoses of Importance in the US and Japan, sponsored by US-Japan Cooperative Program on Development and Utilization of Natural Resources Joint Panel on Toxic Microorganism, and the National Animal Disease Center USDA, ARS, held at Ames, Iowa, Oct. 11-13, 1984

Inhalt
A. Introduction to the Diagnosis of Mycotoxicoses.- 1. Introduction to the diagnosis of mycotoxicoses.- B. Occurrence and Clinical Manifestations of Mycotoxicoses in the United States and Japan.- 2. Occurrence and clinical manifestations of aflatoxicosis.- 3. Occurrence and clinical manifestations of trichothecene toxicoses and zearalenone toxicoses.- 4. Occurrence and clinical manifestations of ochratoxicosis.- 5. Occurrence of penitrem mycotoxins and clinical manifestations of penitrem intoxications.- 6. Occurrence and clinical manifestations of ergot and fescue toxicoses.- 7. Equine leucoencephalomalacia: an historical review.- 8. Occurrence and clinical manifestations of lupinosis and slaframine toxicosis.- 9. Occurrence and clinical manifestations of rubratoxins A & B and cyclopiazonic acid.- C. Comparative Biochemical Changes Associated with the Mycotoxicoses.- 10. Aflatoxin in milk.- 11. Comparative biochemical changes associated with the trichothecene toxicoses.- 12. Comparative biochemical changes associated with mycotoxicoses other than aflatoxicosis and trichothecene toxicosis.- D. Immunologic Changes Associated with Mycotoxicoses.- 13. Immunomodulation in aflatoxicosis.- 14. Immunomodulation in mycotoxicoses other than aflatoxicosis.- 15. Immunochemical methods for diagnosis of mycotoxicoses.- E. Comparative Histopathologic Changes Associated with the Mycotoxicoses.- 16. Comparative histopathologic changes in aflatoxicosis.- 17. Comparative pathologic changes in trichothecene toxicosis.- 18. Comparative pathologic changes in ochratoxicosis and citrinin toxicosis.- 19. Comparative histopathologic changes in cyclopiazonic acid toxicosis and rubratoxicosis.- 20. Fusarium moniliforme and zearalenone toxicoses in domestic animals: a review.- F. Methods of Physical-Chemical Analysis in the Diagnosis of Mycotoxicoses.- 21.A review of TLC and HPLC methods for analysis of aflatoxins in commodities.- 22. Thin-layer and high performance chromatographic methods for analysis of aflatoxins in animal tissues and fluids.- 23. TLC and HPLC methods for analysis of trichothecenes in commodities.- 24. Chromatography of mycotoxins of diagnostic significance other than trichothecenes and aflatoxins.- 25. Principles involved in the analysis of aflatoxin B1 by gas chromatography/mass spectrometry.- 26.Gas chromatography/mass spectral analysis of trichothecenes.- 27. Mass spectroscopy of mycotoxins other than aflatoxins or trichothecenes.- G. Bioassay Systems and their Use in the Diagnosis Of Mycotoxicoses.- 28. Bioassay systems and their use in the diagnosis of mycotoxicoses.- H. Resume and Future Needs in the Diagnosis of Mycotoxicoses.- 29. Resume and future needs in the diagnosis of mycotoxicoses.- Index of scientific names.