This brief highlights nanoparticles used in the diagnosis and treatment of prominent diseases and toxic conditions. Ecofriendly methods which are ideal for the synthesis of medicinally valued nanoparticles are explained and the characteristic features of these particles projected. The role of these particles in the therapeutic field, and the induced biological changes in some diseases are discussed. The main focus is on inflammation, oxidative stress and cellular membrane integrity alterations. The effect of nanoparticles on these changes produced by various agents are highlighted using in vitro and in vivo models. The mechanism of nanoparticles in ameliorating the biological changes is supported by relevant images and data. Finally, the brief demonstrates recent developments on the use of nanoparticles in diagnosis or sensing of some biological materials and biologically hazardous environmental materials.

Includes supplementary material: sn.pub/extras

Autorentext

Dr. T. Devasena is a Nanobiotechnologist currently working as an Associate Professor at the Centre for Nanoscience and Technology, Anna University, Tamil Nadu, India. She has 12 years of teaching experience and 18 years of research experience. She has done intensive research in the area of health and environmental motif of nanotechnology. Her merits in academics and research have earned her many credentials such as reputed international publications and professional recognitions in the form of awards, fellow titles and member titles.

Inhalt

Diagnostic and therapeutic nanomaterials.- Multifunctional Nanoparticles.- Biomarkers.- Diagnostic and therapeutic Techniques.- Toxicity and risk assessment.- In vitro and in vivo applications of selected nanomaterials.