This NATO-ASI installment is designed to provide an advanced overview for doctoral and post-doctoral candidates of the state-of-the-art technologies for bio-detection. The main objective of the work aims at providing readers with the latest developments necessary to successfully understand the CBRN Agents and their associated biotechnologies.

The core methods focused on are mass spectrometry (including chromatographic and electrophoretic separation) and comparisons to spectroscopic, immunological and molecular analysis of chemical, biological and nuclear agents.

The rapid developments in biotechnology New developments in geno proteomics New research on xenobiotics research Tissue imaging using MALDI-MS Field portable mass spectrometry Includes supplementary material: sn.pub/extras

Inhalt

Preface.- Biological agents and bioterrorism.- Immunological Defence Mechanisms against Biological Agents.- Mass spectrometry and tandem mass spectrometry: an overview.- Modern Sample Preparation Techniques for Gas Chromatography-Mass Spectrometry. Analysis of Environmental Markers of Chemical Warfare Agents Use.- An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry and some of its applications.- Field portable mass spectrometry.- MALDI Imaging Mass Spectrometry.- Bacterial Identification by Mass Spectrometry.- Analysis of bio-nanoparticles by means of nano ES in combination with DMA and PDMA intact viruses, virus-like-particles and vaccine particles.- Mass spectrometric target analysis and proteomics in environmental toxicology.- Proteomics for the enhanced discovery of bacterial biomarkers.- Laser-based detection of explosives and related compounds.- Detection of Metals and Radionuclides using Rapid, On-site, Antibody-based Assays.- Identification of Fraudulently Modified Foods.- Tandem mass spectrometric analysis of novel antineoplastic curcumin analogues.- Glycoconjugate vaccines used for prevention from biological agents: Tandem mass spectrometric analysis.- Nano-structured solids and heterogeneous catalysts for the selective decontamination of chemical warfare agents.- Strategic Missile Forces in Ukraine: Brief Survey of Past and Present Environmental Problems.