Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume's first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress both in animal models and humans in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the Genesis and Treatment of Cancer brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field.

Explores the clearly demonstrated link between cytokines and cancer Highlights potential treatment strategies that take advantage of utilizing cytokine and anti-cytokine therapies Contributions from internationally distinguished investigators Covers TNF, IL-2, IL-12, and Type I interferons, among others Practically divided into four useful parts

Klappentext

Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume's first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress both in animal models and humans in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the Genesis and Treatment of Cancer brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field.

Inhalt
Infectious Agents, Cytokines, and Cancer.- Helicobacter pylori and Cytokines in the Genesis of Gastric Cancer.- HTLV-1, Cytokines,and Cancer.- Herpesviruses, Cytokines, and Cancer.- Cytokines and Carcinogenesis.- Tumor Necrosis Factor and Cancer.- Transforming Growth Factor-? and Cancer.- Interleukin-1 Family of Cytokines and Cancer.- Interleukin-4/13 and Cancer.- Interleukin-6 and Castleman's Disease.- Interleukin-10 (IL-10).- Cytokines in Multiple Myeloma.- In Vivo Murine Cytokine Models and the Genesis of Cancer.- Experimental Models of Cytokines and Cancer Prevention.- Cytokines and Tumor Stroma/Metastasis.- Cytokines in the Tumor Stroma.- Cytokines and Tumor Angiogenesis.- Chemokine and Receptor Expression in Tumor Progression.- The Biology of Cancer Cachexia and the Role of TNF-?.- Cytokines in the Treatment of Cancer.- Interleukin-2 and Cancer Therapy.- Interleukin-12 and Cancer Therapy.- The Type I Interferon System With Emphasis on Its Role in Malignancies.- Combination Cytokine Therapy.- Novel Strategies for Cytokine Administration Via Targetting.- Cytokines and Cancer Vaccines.- Anticytokine Treatment.- Cytokines in the Supportive Care of Cancer.