Cured II - LENT Cancer Survivorship Research And Education

Multimodal treatment lies at the heart of the improvement in cancer cure rates. However, the more aggressive the treatment, the more adverse effects in normal tissues can be anticipated. Against this background, a major paradigm shift has taken place in that there is a new focus on cancer survivorship and quality of life: the life worth saving must be worth living. This volume is based on the CURED II conference held in May 2007, which was attended by scientists from many leading institutions. The volume comprises 18 chapters by leading experts who address a variety of important topics relating to late treatment effects, such as mechanisms and evolution of injury, risk factors, the role of screening, options for interventions, second malignancies, and prevention. It is hoped that it will assist the reader in understanding how to prevent and treat the long-term side-effects of irradiation, thus improving the quality of life of long-term survivors of cancer.

Based on the CURED II conference held in May 2007, which was attended by scientists from many leading institutions Addresses a variety of important topics relating to late treatment effects, such as mechanisms of injury, risk factors, the role of screening, and second malignancies Clearly explains appropriate strategies for the prevention and treatment of late effects Includes supplementary material: sn.pub/extras

Zusammenfassung

From the reviews:

"The book examines mechanisms of action and causes of both early and late radiotherapy consequences. ... Written for oncologists, particularly radiation oncologists, the book is appropriate for attendings, residents, and fellows in all oncology specialties. The authors/contributors are world leaders in oncology. ... This is a very well organized and written book, succinct yet strikingly informative. This series should be in every radiation oncologist's personal library and is full of insight for those in other oncology specialties." (James G. Douglas, Doody's Review Service, June, 2009)

"There are 14 chapters written by well-known experts in the field: all of whom share the common target of striving to describe, how cancer patients can be cured by radiation therapy, chemotherapy and biological adjuvants. ... This is very important when one considers time and life spans of patient cohorts ... . Not only the radiotherapist but also the clinicians and all those who take care of cancer patients will appreciate ... this book." (Giampiero Beluffi, La Radiologia Media, Vol. 114, 2009)

"Cured II.LENT Cancer Survivorship Research and Education is the second volume concerning late effects of radiation therapy in normal tissues. ... The text covers a larger range of issues, both physical and biological, written by notable experts in the field of radiobiology. ... provide invaluable information for training and practising oncologists. Thoroughly recommended reading material." (John Glaholm, RAD Magazine, November, 2010)

Inhalt
Concured: Defining the Leading Edge in Research of Adverse Effects of Treatment for Adult-Onset Cancers.- Bioimaging In Vivo to Discern the Evolution of Late Effects Temporally and Spatially.- Association Between Single Nucleotide Polymorphisms and Susceptibility for the Development of Adverse Effects Resulting from Radiation Therapy.- Prospective Second-Cancer Risk Estimation for Contemporary Radiotherapeutic Protocols.- Bioengineering in the Repair of Irradiated Normal Tissue by Bone Marrow Derived Stem Cell Populations.- Development of a Queriable Database for Oncology Outcome Analysis.- Post-Radiation Dysphagia.- Lithium as a Differential Neuroprotector During Brain Irradiation.- Risks and Surveillance of Second Malignant Tumors in Prostate and Bladder Cancer Survivors.- Cardiotoxic Effects of Radiation Therapy in Hodgkin's Lymphoma and Breast Cancer Survivors and the Potential Mitigating Effects of Exercise.- Biodetection and Biointervention: Cytokine Pathways as a Rationale for Anticytokine Interventions Post-Radiation.- Late Toxicity from Hypofractionated Stereotactic Body Radiation.- The Radiation Spectrum of Normal Tissue Toxicity and Tolerance Multiorgan Domino Effect.- Risk Factors for Second Malignancies Following Stem Cell Transplant.