This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing various aspects of COVID-19 infection, including global epidemiology, genome organization, immunopathogenesis, transmission cycle, diagnosis, treatment, prevention, and control strategies, it highlights host-pathogen interactions, host immune response, and pathogen immune invasion strategies toward developing an immune intervention or preventive vaccine for COVID-19.

An understanding of the topics covered in the book is imperative in the context of designing strategies to protect the human race from further losses and harm due to SARS-CoV-2 infection causing COVID-19.

Provides collated information on novel coronavirus (SARS-CoV-2) biology, including replication, genetics, and pathogenesis Discusses the pathogenesis of various emerging and re-emerging SARS coronaviruses Summarizes prevention with potential therapeutics against novel SARS-CoV-2 and COVID-19. Highlights prevention and control strategies for COVID-19 and novel SARS-CoV-2 infection Reviews the host-pathogen interaction, host immune response and clinical manifestation of the human Coronavirus disease COVID-19

Autorentext
Prof. (Dr.) Shailendra K. Saxena is a Vice Dean and Professor at King George's Medical University, Lucknow. His primary research interest is to understand the molecular mechanisms of host defense during human viral infections and to develop predictive, preventive and therapeutic strategies against these diseases. Prof. Saxena's work has been published in various high impact factor reputed international journals. He has been honored by several prestigious National and International Awards, Fellowships and Scholarships in India and abroad, including Young Scientist Awards, BBSRC India Partnering Award and named as the Global Leader in Science by The Scientist magazine (USA) and International Opinion Leader/Expert that are involved in the vaccination for JE by IPIC (UK). He has been elected Fellow of The Royal Society of Biology UK (FRSB), The Royal Society of Chemistry UK (FRSC), The Academy of Environmental Biology, India (FAEB), Indian Virological Society (FIVS), The Biotech Research Society, India (FBRS); and Fellowship of the (European) Academy of Translational Medicine Professionals, Austria (FacadTM). He has been awarded Dr. JC Bose National Award of Department of Biotechnology (DBT, Min. of Science & Technology, Govt. of India) in Biotechnology and has an active collaboration with various US universities.

Inhalt

Module 1 Global trends in epidemiology of Coronavirus Disease 2019 (COVID-19).- Module 2 Genome organization and Pathogenesis of novel Coronavirus 2019 (SARS-CoV-2).- Module 3 Host immune response against human SARS-CoV-2 infection.- Module 4 Emergence and Re-emergence of SARS Coronaviruses.- Module 5 Transmission cycle of SARS-CoV and SARS-CoV-2.- Module 6 Preparing for the perpetual challenges of pandemics of Coronavirus infections with special focus on SARS-CoV-2. Module 7 Clinical manifestations and diagnosis of human SARS-CoV-2 infection ** .- Module 8 Treatment and Drugs for SARS-CoV-2.- Module 9_** Prevention and control strategies for SARS-CoV-2 infection.