Target Organ Toxicity, Volume I

Klappentext

Offers information on the general principles of target organ toxicity. This book explores pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry.

Zusammenfassung
This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively

Inhalt

VOLUME I:
Basic Principles of Target Organ Toxicity. Role of Pharmacokinetics in Rationalizing Tissue Distortion. Role of Metabolic Activation in Target Organ Toxicity. Role of Excretion. Species Variation in Target Organ Toxicity. Importance of Tissue-Specific Biochemistry in Determination of Target Organ Toxicity. Role of Key Defense Systems in Target Organ Toxicity. Liver as a Organ for Toxicity. Index.